Health Technology/clinical-trials

TELEHEART Trial Opens: Telemedicine vs Standard Care for Heart Failure Medication Optimisation — What Clinicians Need to Know

247 Health News Editorial

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10 Apr 2026

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4 min read

·clinical-trials

The TELEHEART trial is investigating whether telemedicine-guided follow-up improves medication optimisation in newly diagnosed heart failure patients compared to standard care. This Italian study could reshape post-discharge heart failure management globally.

Originally reported by ClinicalTrials.gov

References

  1. 1.Azienda Unita Sanitaria Locale di Piacenza. (2024). TELEHEART Trial: Telemedicine-guided Uptitration of Therapy in Chronic Heart Failure. ClinicalTrials.gov. https://clinicaltrials.gov/study/NCT07518030
  2. 2.Greene, S. J., Butler, J., Albert, N. M., DeVore, A. D., Sharma, P. P., Duffy, C. I., Hill, C. L., McCague, K., Mi, X., Patterson, J. H., Spertus, J. A., Thomas, L., Williams, F. B., Hernandez, A. F., & Fonarow, G. C. (2018). Medical therapy for heart failure with reduced ejection fraction: the CHAMP-HF registry. Journal of the American College of Cardiology, 72(4), 351-366. https://doi.org/10.1016/j.jacc.2018.04.014
  3. 3.Dharmarajan, K., Hsieh, A. F., Lin, Z., Bueno, H., Ross, J. S., Horwitz, L. I., Barreto-Filho, J. A., Kim, N., Bernheim, S. M., Suter, L. G., Drye, E. E., & Krumholz, H. M. (2013). Diagnoses and timing of 30-day readmissions after hospitalization for heart failure, acute myocardial infarction, or pneumonia. JAMA, 309(4), 355-363. https://doi.org/10.1001/jama.2013.6056
  4. 4.Heidenreich, P. A., Bozkurt, B., Aguilar, D., Allen, L. A., Byun, J. J., Colvin, M. M., Deswal, A., Drazner, M. H., Dunlay, S. M., Evers, L. R., Fang, J. C., Fedson, S. E., Fonarow, G. C., Hayek, S. S., Hernandez, A. F., Khazanie, P., Kittleson, M. M., Lee, C. S., Link, M. S., ... & Yancy, C. W. (2022). 2022 AHA/ACC/HFSA guideline for the management of heart failure. Journal of the American College of Cardiology, 79(17), e263-e421. https://doi.org/10.1016/j.jacc.2021.12.012
  5. 5.National Heart Foundation of Australia. (2023). Heart failure management from specialist to primary care: a practical approach. Medical Journal of Australia, 218(8), 334-340. https://doi.org/10.5694/mja2.51956
  6. 6.Komajda, M., Böhm, M., Borer, J. S., Ford, I., Tavazzi, L., Pannaux, M., Swedberg, K., & SHIFT Investigators. (2014). Incremental benefit of drug therapies for chronic heart failure over 65 years: a network meta-analysis. Heart, 100(18), 1430-1440. https://doi.org/10.1136/heartjnl-2014-305718
  7. 7.Ziaeian, B., & Fonarow, G. C. (2016). The prevention of hospital readmissions in heart failure. Progress in Cardiovascular Diseases, 58(4), 379-385. https://doi.org/10.1016/j.pcad.2016.01.006
  8. 8.Koehler, F., Winkler, S., Schieber, M., Sechtem, U., Stangl, K., Böhm, M., Boll, H., Baumann, G., Honold, M., Koehler, K., Gelbrich, G., Kirwan, B. A., Anker, S. D., & Telemedical Interventional Monitoring in Heart Failure Investigators. (2018). Impact of remote telemedical management on mortality and hospitalizations in ambulatory patients with chronic heart failure. Circulation, 123(17), 1873-1880. https://doi.org/10.1161/CIRCULATIONAHA.117.029968
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247 Health News Editorial

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