Health Technology/clinical-trials

Spanish e-Perinatal Trial Tests Early Mental Health Referral Strategy for Pregnant and Postpartum Women — Implementation Study Opens

247 Health News Editorial

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11 June 2026

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3 min read

·clinical-trials

Spanish researchers launch major implementation study testing early detection and referral strategies for perinatal depression and anxiety. The e-Perinatal trial combines mobile health technology with routine maternal care to improve access to specialized mental health services for 3,000 pregnant and postpartum women.

Originally reported by ClinicalTrials.gov

References

  1. 1.University of Seville. (2024). Feasibility, acceptability, and preliminary effectiveness of early referral strategy to specialized mental health services: An embedded implementation study. ClinicalTrials.gov. https://clinicaltrials.gov/study/NCT07609550
  2. 2.Woody, C. A., Ferrari, A. J., Siskind, D. J., Whiteford, H. A., & Harris, M. G. (2017). A systematic review and meta-regression of the prevalence and incidence of perinatal depression. Journal of Affective Disorders, 219, 86-92. https://doi.org/10.1016/j.jad.2017.05.003
  3. 3.Curran, G. M., Bauer, M., Mittman, B., Pyne, J. M., & Stetler, C. (2012). Effectiveness-implementation hybrid designs: combining elements of clinical effectiveness and implementation research to enhance public health impact. Medical Care, 50(3), 217-226. https://doi.org/10.1097/MLR.0b013e3182408812
  4. 4.Loudon, K., Treweek, S., Sullivan, F., Donnan, P., Thorpe, K. E., & Zwarenstein, M. (2015). The PRECIS-2 tool: designing trials that are fit for purpose. BMJ, 350, h2147. https://doi.org/10.1136/bmj.h2147
  5. 5.Dennis, C. L., Falah-Hassani, K., & Shiri, R. (2017). Prevalence of antenatal and postnatal anxiety: systematic review and meta-analysis. British Journal of Psychiatry, 210(5), 315-323. https://doi.org/10.1192/bjp.bp.116.187179
  6. 6.Stein, A., Pearson, R. M., Goodman, S. H., Rapa, E., Rahman, A., McCallum, M., ... & Pariante, C. M. (2014). Effects of perinatal mental disorders on the fetus and child. The Lancet, 384(9956), 1800-1819. https://doi.org/10.1016/S0140-6736(14)61277-0
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