Health Technology/clinical-trials

SLEEP-BOOST Trial Opens: Digital CBT-I vs Sleep Education in Older Surgical Patients — Targeting Postoperative Delirium Prevention

247 Health News Editorial

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17 Apr 2026

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4 min read

·clinical-trials

The SLEEP-BOOST pilot trial investigates digital cognitive behavioural therapy for insomnia in older adults undergoing joint replacement surgery. This innovative approach targets preoperative sleep optimization to prevent postoperative delirium and neurocognitive complications.

Originally reported by ClinicalTrials.gov

References

  1. 1.Massachusetts General Hospital. (2024). A Pilot Study of Digital Sleep Optimization for Brain Health Outcomes in Older Surgical Patients (SLEEP-BOOST). ClinicalTrials.gov. NCT06375265. https://clinicaltrials.gov/study/NCT06375265
  2. 2.Inouye, S. K., Westendorp, R. G., & Saczynski, J. S. (2014). Delirium in elderly people. The Lancet, 383(9920), 911-922. https://doi.org/10.1016/S0140-6736(13)60688-1
  3. 3.Flink, B. J., Rivelli, S. K., Cox, E. A., White, W. D., Falcone, G., Vail, T. P., ... & Browndyke, J. N. (2012). Obstructive sleep apnea and incidence of postoperative delirium after elective knee replacement in the nondemented elderly. Anesthesiology, 116(4), 788-796. https://doi.org/10.1097/ALN.0b013e31824b94fc
  4. 4.Evered, L., Silbert, B., Knopman, D. S., Scott, D. A., DeKosky, S. T., Rasmussen, L. S., ... & Nomenclature Consensus Working Group. (2018). Recommendations for the nomenclature of cognitive change associated with anaesthesia and surgery—2018. British Journal of Anaesthesia, 121(5), 1005-1012. https://doi.org/10.1016/j.bja.2017.11.087
  5. 5.Ritterband, L. M., Thorndike, F. P., Ingersoll, K. S., Lord, H. R., Gonder-Frederick, L., Frederick, C., ... & Morin, C. M. (2017). Effect of a web-based cognitive behavior therapy for insomnia intervention with 1-year follow-up: a randomized clinical trial. JAMA Psychiatry, 74(1), 68-75. https://doi.org/10.1001/jamapsychiatry.2016.3249
  6. 6.Beswick, A. D., Wylde, V., Gooberman-Hill, R., Blom, A., & Dieppe, P. (2012). What proportion of patients report long-term pain after total hip or knee replacement for osteoarthritis? A systematic review of prospective studies in unselected patients. BMJ Open, 2(1), e000435. https://doi.org/10.1136/bmjopen-2011-000435
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