Health Technology/clinical-trials

Remote Wearable Technology Study Investigates Hidden Cardiac Risk Factors in Duchenne Muscular Dystrophy — Novel Approach to DMD Cardiomyopathy Prevention

247 Health News Editorial

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8 June 2026

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4 min read

·clinical-trials

New remote monitoring study uses wearable technology to investigate hidden cardiovascular risk factors in Duchenne muscular dystrophy. Research examines hyperglycemia and heart rate variability as potential contributors to DMD cardiomyopathy, the leading cause of death in these patients.

Originally reported by ClinicalTrials.gov

References

  1. 1.Vanderbilt University Medical Center. (2024). Wearable Technology to Evaluate Hyperglycemia and Heart Rate Variability in Duchenne Muscular Dystrophy. ClinicalTrials.gov. https://clinicaltrials.gov/study/NCT06124196
  2. 2.Birnkrant, D. J., Bushby, K., Bann, C. M., Apkon, S. D., Blackwell, A., Brumbaugh, D., Case, L. E., Clemens, P. R., Hadjiyannakis, S., Pandya, S., Street, N., Tomezsko, J., Wagner, K. R., Ward, L. M., Weber, D. R., & DMD Care Considerations Working Group. (2018). Diagnosis and management of Duchenne muscular dystrophy, part 2: respiratory, cardiac, bone health, and orthopaedic management. The Lancet Neurology, 17(4), 347-361. https://doi.org/10.1016/S1474-4422(18)30025-5
  3. 3.Ryder, S., Leadley, R. M., Armstrong, N., Westwood, M., de Kock, S., Butt, T., Jain, M., & Kleijnen, J. (2017). The burden, epidemiology, costs and treatment for Duchenne muscular dystrophy: an evidence review. Orphanet Journal of Rare Diseases, 12(1), 79. https://doi.org/10.1186/s13023-017-0631-3
  4. 4.Shaffer, F., & Ginsberg, J. P. (2017). An overview of heart rate variability metrics and norms. Frontiers in Public Health, 5, 258. https://doi.org/10.3389/fpubh.2017.00258
  5. 5.Rodger, S., Woods, K. L., Bladen, C. L., Stringer, A., Vry, J., Gramsch, K., Kirschner, J., Thompson, R., Bushby, K., & Lochmüller, H. (2015). Adult care for Duchenne muscular dystrophy in the UK. Journal of Neurology, 262(3), 629-641. https://doi.org/10.1007/s00415-015-7733-2
  6. 6.Thayer, J. F., Yamamoto, S. S., & Brosschot, J. F. (2010). The relationship of autonomic imbalance, heart rate variability and cardiovascular disease risk factors. International Journal of Cardiology, 141(2), 122-131. https://doi.org/10.1016/j.ijcard.2009.09.543
  7. 7.Bello, L., Gordish-Dressman, H., Morgenroth, L. P., Henricson, E. K., Duong, T., Hoffman, E. P., Cnaan, A., McDonald, C. M., & CINRG Investigators. (2015). Prednisone/prednisolone and deflazacort regimens in the CINRG Duchenne Natural History Study. Neurology, 85(12), 1048-1055. https://doi.org/10.1212/WNL.0000000000001950
  8. 8.Kamdar, F., & Garry, D. J. (2016). Dystrophin-deficient cardiomyopathy. Journal of the American College of Cardiology, 67(21), 2533-2546. https://doi.org/10.1016/j.jacc.2016.02.081
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