Randomised Trial Launches: Personalised Digital Lifestyle Program With Virtual Coach and CGM Integration Targets HbA1c Reduction in Type 2 Diabetes — Key Design Details for Clinicians
247 Health News Editorial
·6 July 2026
·4 min read
·clinical-trialsA new randomised trial from the University of Twente will test whether a personalised digital lifestyle program — with or without virtual coaching and continuous glucose monitoring — can meaningfully reduce HbA1c in metformin-managed adults with type 2 diabetes over 24 months. The 160-participant study offers a rare head-to-head comparison of program components, with results expected by December 2028.
Originally reported by ClinicalTrials.gov
References
- 1.University of Twente. (2025). An online personalised lifestyle program with a virtual AI lifestyle coach in combination with continues glucose monitoring for people with type 2 diabetes (NCT07661381). ClinicalTrials.gov. https://clinicaltrials.gov/study/NCT07661381
- 2.Knowler, W. C., Barrett-Connor, E., Fowler, S. E., Hamman, R. F., Lachin, J. M., Walker, E. A., & Nathan, D. M. (2002). Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. New England Journal of Medicine, 346(6), 393–403. https://doi.org/10.1056/NEJMoa012512
- 3.Galaviz, K. I., Narayan, K. M. V., Lobelo, F., & Weber, M. B. (2018). Lifestyle and the prevention of type 2 diabetes: A status report. American Journal of Lifestyle Medicine, 12(1), 4–20. https://doi.org/10.1177/1559827615619159
- 4.Ida, S., Kaneko, R., & Murata, K. (2019). Utility of real-time and retrospective continuous glucose monitoring in patients with type 2 diabetes: A meta-analysis of randomized controlled trials. Journal of Diabetes Research, 2019, Article 4684815. https://doi.org/10.1155/2019/4684815
- 5.Sun, H., Saeedi, P., Karuranga, S., Pinkepank, M., Ogurtsova, K., Duncan, B. B., Stein, C., Basit, A., Chan, J. C. N., Mbanya, J. C., Pavkov, M. E., Ramachandaran, A., Wild, S. H., James, S., Herman, W. H., Zhang, P., Bommer, C., Kuo, S., Boyko, E. J., & Magliano, D. J. (2022). IDF Diabetes Atlas: Global, regional and country-level diabetes prevalence estimates for 2021 and projections for 2045. Diabetes Research and Clinical Practice, 183, Article 109119. https://doi.org/10.1016/j.diabres.2021.109119
- 6.Pal, K., Eastwood, S. V., Michie, S., Farmer, A., Barnard, M. L., Peacock, R., Wood, B., Edwards, P., & Murray, E. (2014). Computer-based interventions to improve self-management in adults with type 2 diabetes: A systematic review and meta-analysis. Diabetes Care, 37(6), 1759–1766. https://doi.org/10.2337/dc13-1386
2
247 Health News Editorial
247 Health News is a medical intelligence platform delivering evidence-based research appraisals, clinical trial monitoring, and health technology news for healthcare professionals.
Related Articles
clinical-trials
Digital Health Platform vs Case Manager Support in Hypertension Management: Taiwan's 1,726-Participant Trial Signals a Shift in Blood Pressure Care Delivery
3 Aug 2026
clinical-trials
Phase II Trial: AI-Powered Wysa Chatbot vs Unmet Need — Digital Eating Disorder Prevention in At-Risk Adolescents
3 Aug 2026
clinical-trials
Pilot Trial Targets the Inpatient-to-Outpatient Gap: Digital Smoking Cessation Intervention for Persons With Serious Mental Illness — Key Findings for Clinicians
3 Aug 2026
This content is for educational purposes for healthcare professionals only and does not constitute clinical advice. Clinical decisions should be based on individual patient assessment, current guidelines, and appropriate specialist consultation. Editorial Standards · Privacy Policy · Terms of Service