Health Technology/clinical-trials

Randomised Trial Launches in Ethiopia: Video-Based Education and SMS Reminders Versus Standard Care for TB Preventive Therapy Initiation and Completion Among Household Contacts

247 Health News Editorial

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25 July 2026

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5 min read

·clinical-trials

A new interventional trial in South Ethiopia is testing whether video-based education combined with SMS reminders can improve tuberculosis preventive therapy initiation and completion among household contacts of index TB cases. With 304 participants enrolled and results expected by late 2026, the study addresses a critical gap in the global End TB strategy. Clinicians working in TB-endemic settings and high-risk migrant populations should watch this space.

Originally reported by ClinicalTrials.gov

References

  1. 1.Arba Minch University. (2025). Digital health intervention in improving preventive treatment initiation and completion among close contacts of tuberculosis patients in South Ethiopia (NCT07313995). ClinicalTrials.gov. https://clinicaltrials.gov/study/NCT07313995
  2. 2.World Health Organization. (2020). WHO consolidated guidelines on tuberculosis. Module 1: Prevention — tuberculosis preventive treatment. World Health Organization. https://www.who.int/publications/i/item/9789240001503
  3. 3.World Health Organization. (2024). Global tuberculosis report 2024. World Health Organization. https://www.who.int/teams/global-tuberculosis-programme/tb-reports/global-tuberculosis-report-2024
  4. 4.Ngwatu, B. K., Nseka, N. P., Ecosse, E., Blok, N., Auer, C., Lutumba, P., Kashongwe, Z., & Hermans, S. (2018). The impact of digital health technologies on tuberculosis treatment: a systematic review. European Respiratory Journal, 51(3), 1700038. https://doi.org/10.1183/13993003.00038-2017
  5. 5.Gebremariam, M. K., Bjune, G. A., & Frich, J. C. (2010). Barriers and facilitators of adherence to TB treatment in patients on concomitant TB and HIV treatment: a qualitative study. BMC Infectious Diseases, 10, 261. https://doi.org/10.1186/1471-2334-10-261
  6. 6.Alsdurf, H., Hill, P. C., Matteelli, A., Getahun, H., & Menzies, D. (2016). The cascade of care in diagnosis and treatment of latent tuberculosis infection: a systematic review and meta-analysis. The Lancet Infectious Diseases, 16(11), 1269–1278. https://doi.org/10.1016/S1473-3099(16)30216-X
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247 Health News Editorial

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