QUIT-Mobile Trial: mHealth Self-Monitoring Added to Brief Intervention Targets Sustained Drug Use Reduction in Primary Care — Key Findings for Clinicians
247 Health News Editorial
·29 July 2026
·5 min read
·clinical-trialsThe completed QUIT-Mobile RCT tested whether weekly mHealth self-monitoring and automated feedback could enhance and sustain the effects of a validated primary care brief intervention for risky drug use over 12 months. Conducted across federally qualified health centres in Southern California, the trial enrolled 458 low-income, predominantly Latino adults with moderate-risk drug use — a population with significant unmet need between prevention and specialist treatment. Results are anticipated to have direct implications for scalable, technology-augmented substance use care in primary care settings globally.
Originally reported by ClinicalTrials.gov
References
- 1.University of California, Los Angeles. (2021). mHealth to enhance & sustain drug use reduction of the QUIT BI in primary care (NCT04935606). ClinicalTrials.gov. https://clinicaltrials.gov/study/NCT04935606
- 2.Gelberg, L., Andersen, R. M., Afifi, A. A., Leake, B. D., Arangua, L., Vahidi, M., Singleton, K., Yacenda-Murphy, J., Dube-Scherr, L., Carter, M. F., & Baumeister, S. E. (2015). Project QUIT (Quit Using Drugs Intervention Trial): a randomized controlled trial of a primary care-based multi-component brief intervention to reduce risky drug use. Addiction, 110(11), 1777–1790. https://doi.org/10.1111/add.12778
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- 4.Humeniuk, R., Ali, R., Babor, T. F., Farrell, M., Formigari, R., Jittiwutikarn, J., de Lacerda, R. B., Ling, W., Marsden, J., Monteiro, M., Nhiwatiwa, S., Pal, H., Poznyak, V., & Simon, S. (2008). Validation of the Alcohol, Smoking And Substance Involvement Screening Test (ASSIST). Addiction, 103(6), 1039–1047. https://doi.org/10.1111/j.1360-0443.2007.02114.x
- 5.Curran, G. M., Bauer, M., Mittman, B., Pyne, J. M., & Stetler, C. (2012). Effectiveness-implementation hybrid designs: combining elements of clinical effectiveness and implementation research to enhance public health impact. Medical Care, 50(3), 217–226. https://doi.org/10.1097/MLR.0b013e3182408812
- 6.Tofighi, B., Abrantes, A., & Stein, M. D. (2018). The role of technology-based interventions for substance use disorders in primary care: a review of the literature. Medical Clinics of North America, 102(4), 715–731. https://doi.org/10.1016/j.mcna.2017.11.010
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247 Health News Editorial
247 Health News is a medical intelligence platform delivering evidence-based research appraisals, clinical trial monitoring, and health technology news for healthcare professionals.
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