Prospective Cohort Study Evaluates Machine Learning Risk Stratification for Extrahepatic Metastasis in Hepatocellular Carcinoma — Real-World Implementation Data

References

1. 1.Chen, J. H., & Asch, S. M. (2017). Machine learning and prediction in medicine—beyond the peak of inflated expectations. New England Journal of Medicine, 376(26), 2507-2509. https://doi.org/10.1056/NEJMp1702071
2. 2.European Association for the Study of the Liver. (2018). EASL Clinical Practice Guidelines: Management of hepatocellular carcinoma. Journal of Hepatology, 69(1), 182-236. https://doi.org/10.1016/j.jhep.2018.03.019
3. 3.Llovet, J. M., Kelley, R. K., Villanueva, A., Singal, A. G., Pikarsky, E., Roayaie, S., Lencioni, R., Koike, K., Zucman-Rossi, J., & Finn, R. S. (2021). Hepatocellular carcinoma. Nature Reviews Disease Primers, 7(1), 6. https://doi.org/10.1038/s41572-020-00240-3
4. 4.Marrero, J. A., Kulik, L. M., Sirlin, C. B., Zhu, A. X., Finn, R. S., Abecassis, M. M., Roberts, L. R., & Heimbach, J. K. (2018). Diagnosis, staging, and management of hepatocellular carcinoma: 2018 practice guidance by the American Association for the Study of Liver Diseases. Hepatology, 68(2), 723-750. https://doi.org/10.1002/hep.29913
5. 5.Rajkomar, A., Dean, J., & Kohane, I. (2019). Machine learning in medicine. New England Journal of Medicine, 380(14), 1347-1358. https://doi.org/10.1056/NEJMra1814259
6. 6.Singal, A. G., Lampertico, P., & Nahon, P. (2020). Epidemiology and surveillance for hepatocellular carcinoma: New trends. Journal of Hepatology, 72(2), 250-261. https://doi.org/10.1016/j.jhep.2019.08.025
7. 7.Therapeutic Goods Administration. (2023). Software as Medical Device: Guidance for manufacturers. TGA Guidelines. https://www.tga.gov.au/resources/resource/guidance/software-medical-device-guidance-manufacturers
8. 8.Tongji Hospital. (2024). Prospective Evaluation of a Locked Risk-Stratified Surveillance Strategy for Extrahepatic Metastasis in Hepatocellular Carcinoma. ClinicalTrials.gov. https://clinicaltrials.gov/study/NCT07444905
9. 9.Topol, E. J. (2019). High-performance medicine: the convergence of human and artificial intelligence. Nature Medicine, 25(1), 44-56. https://doi.org/10.1038/s41591-018-0300-7
10. 10.Vogel, A., Meyer, T., Sapisochin, G., Salem, R., & Saborowski, A. (2022). Hepatocellular carcinoma. The Lancet, 400(10360), 1345-1362. https://doi.org/10.1016/S0140-6736(22)01200-4