PRIORITY Study Launches: Integrated Molecular-Digital Model for Cervical Cancer Screening — Implications for Australian Practice
247 Health News Editorial
·27 May 2026
·4 min read
·clinical-trialsThe PRIORITY study evaluates an innovative integrated molecular and digital model for cervical cancer screening, combining HPV self-sampling with telemedicine-supported colposcopy. This Chilean multicenter observational study could reshape screening approaches globally.
Originally reported by ClinicalTrials.gov
References
- 1.Pontificia Universidad Catolica de Chile. (2024). The PRIORITY Study in Cervical Cancer: A Prospective Multicenter Observational Evaluation. ClinicalTrials.gov. NCT07593066. https://clinicaltrials.gov/study/NCT07593066
- 2.Perkins, R. B., Guido, R. S., Castle, P. E., Chelmow, D., Einstein, M. H., Garcia, F., Huh, W. K., Kim, J. J., Moscicki, A. B., Nayar, R., Saraiya, M., Sawaya, G. F., Wentzensen, N., Schiffman, M., & 2019 ASCCP Risk-Based Management Consensus Guidelines Committee. (2020). 2019 ASCCP Risk-Based Management Consensus Guidelines for abnormal cervical cancer screening tests and cancer precursors. Journal of Lower Genital Tract Disease, 24(2), 102-131. https://doi.org/10.1097/LGT.0000000000000525
- 3.Louwers, J. A., Zaal, A., Kocken, M., ter Harmsel, W. A., Graziosi, G. C., Spruijt, J. W., Berkhof, J., Balas, C., & Papagiannakis, E. (2011). Dynamic spectral imaging colposcopy: higher sensitivity for detection of premalignant cervical lesions. BJOG, 118(3), 309-318. https://doi.org/10.1111/j.1471-0528.2011.02932.x
- 4.Schiffman, M., Doorbar, J., Wentzensen, N., de Sanjosé, S., Fakhry, C., Monk, B. J., Stanley, M. A., & Franceschi, S. (2016). Carcinogenic human papillomavirus infection. Nature Reviews Disease Primers, 2, 16086. https://doi.org/10.1038/nrdp.2016.86
- 5.Fontham, E. T., Wolf, A. M., Church, T. R., Etzioni, R., Flowers, C. R., Herzig, A., Guerra, C. E., Oeffinger, K. C., Shih, Y. C. T., Walter, L. C., Kim, J. J., Andrews, K. S., DeSantis, C. E., Fedewa, S. A., Manassaram-Baptiste, D., Saslow, D., Wender, R. C., & Smith, R. A. (2020). Cervical cancer screening for individuals at average risk: 2020 guideline update from the American Cancer Society. CA: A Cancer Journal for Clinicians, 70(5), 321-346. https://doi.org/10.3322/caac.21628
- 6.Sung, H., Ferlay, J., Siegel, R. L., Laversanne, M., Soerjomataram, I., Jemal, A., & Bray, F. (2021). Global Cancer Statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA: A Cancer Journal for Clinicians, 71(3), 209-249. https://doi.org/10.3322/caac.21660
- 7.Canfell, K., Kim, J. J., Brisson, M., Keane, A., Simms, K. T., Caruana, M., Burger, E. A., Martin, D., Nguyen, D. T. N., Bénard, É., Sy, S., Regan, C., Drolet, M., Gingras, G., Laprise, J. F., Torode, J., Smith, M. A., Fidarova, E., Trapani, D., ... Hutubessy, R. (2020). Mortality impact of achieving WHO cervical cancer elimination targets: a comparative modelling analysis in 78 low-income and lower-middle-income countries. New England Journal of Medicine, 383(6), 549-559. https://doi.org/10.1056/NEJMoa1909006
- 8.Arbyn, M., Weiderpass, E., Bruni, L., de Sanjosé, S., Saraiya, M., Ferlay, J., & Bray, F. (2020). Estimates of incidence and mortality of cervical cancer in 2018: a worldwide analysis. The Lancet Global Health, 8(2), e191-e203. https://doi.org/10.1016/S2214-109X(19)30482-6
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