Pilot Trial Targets Financial Toxicity in Adolescent and Young Adult Cancer Survivors: AYA-NAV Digital Navigation Intervention Now Recruiting
247 Health News Editorial
·24 July 2026
·4 min read
·clinical-trialsColumbia University's AYA-NAV pilot trial is now recruiting adolescent and young adult cancer survivors aged 15–39 to evaluate a hybrid digital and human navigation intervention targeting financial toxicity and health-related social needs. The study integrates the Findhelp.org platform with structured person-to-person support, measuring feasibility and preliminary impact on financial distress using the validated COST instrument. Results are anticipated by mid-2027 and could inform a future definitive trial in this underserved oncology population.
Originally reported by ClinicalTrials.gov
References
- 1.Columbia University. (2025). Navigating financial and health-related social needs in adolescent and young adult cancer survivors (AYA-NAV): A digital intervention pilot study (NCT06950983). ClinicalTrials.gov. https://clinicaltrials.gov/study/NCT06950983
- 2.de Souza, J. A., Yap, B. J., Wroblewski, K., Blinder, V., Araújo, F. S., Hlubocky, F. J., & Daugherty, C. K. (2017). Measuring financial toxicity as a clinically relevant patient-reported outcome: The validation of the Comprehensive Score for financial Toxicity (COST). Cancer, 123(3), 476–484. https://doi.org/10.1002/cncr.30369
- 3.Keegan, T. H. M., Ries, L. A. G., Barr, R. D., Geiger, A. M., Dahlke, D. V., Pollock, B. H., & Bleyer, A. (2016). Comparison of cancer survival trends in the United States of adolescents and young adults with those in children and older adults. Cancer, 122(7), 1009–1016. https://doi.org/10.1002/cncr.29869
- 4.Parsons, H. M., Harlan, L. C., Lynch, C. F., Hamilton, A. S., Wu, X. C., Kato, I., & Keegan, T. H. M. (2012). Impact of cancer on work and education among adolescent and young adult cancer survivors. Journal of Clinical Oncology, 30(19), 2393–2400. https://doi.org/10.1200/JCO.2011.39.6333
- 5.Zafar, S. Y., & Abernethy, A. P. (2013). Financial toxicity, Part I: A new name for a growing problem. Oncology (Williston Park), 27(2), 80–149. https://www.cancernetwork.com/view/financial-toxicity-part-i-new-name-growing-problem
- 6.Zheng, Z., Han, X., Guy, G. P., Davidoff, A. J., Li, C., Banegas, M. P., & Ekwueme, D. U. (2019). Do cancer survivors change their prescription drug use for cost reasons? Findings from a nationally representative sample in the United States. Cancer, 125(4), 604–611. https://doi.org/10.1002/cncr.31560
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