Pilot Trial Opens: Telehealth CBT-I Adapted for Ulcerative Colitis Patients — Addressing the Sleep-IBD Connection
247 Health News Editorial
·12 May 2026
·3 min read
·clinical-trialsA pilot study is testing telehealth-delivered cognitive behavioral therapy for insomnia specifically adapted for ulcerative colitis patients. This novel approach addresses the significant sleep disturbances affecting up to 70% of IBD patients.
Originally reported by ClinicalTrials.gov
References
- 1.Ananthakrishnan, A. N., Long, M. D., Martin, C. F., Sandler, R. S., & Kappelman, M. D. (2013). Sleep disturbance and risk of active disease in patients with Crohn's disease and ulcerative colitis. Clinical Gastroenterology and Hepatology, 11(8), 965-971. https://doi.org/10.1016/j.cgh.2013.01.021
- 2.Dartmouth-Hitchcock Medical Center. (2024). Piloting an insomnia treatment in patients with ulcerative colitis. ClinicalTrials.gov. NCT07428629. https://clinicaltrials.gov/study/NCT07428629
- 3.Julious, S. A. (2005). Sample size of 12 per group rule of thumb for a pilot study. Pharmaceutical Statistics, 4(4), 287-291. https://doi.org/10.1002/pst.185
- 4.Keefer, L., Stepanski, E. J., Ranjbaran, Z., Benson, L. M., & Keshavarzian, A. (2006). An initial report of sleep disturbance in inactive inflammatory bowel disease. Journal of Clinical Sleep Medicine, 2(4), 409-416. https://doi.org/10.5664/jcsm.26506
- 5.Morin, C. M., Bootzin, R. R., Buysse, D. J., Edinger, J. D., Espie, C. A., & Lichstein, K. L. (2006). Psychological and behavioral treatment of insomnia: update of the recent evidence. Sleep, 29(11), 1398-1414. https://doi.org/10.1093/sleep/29.11.1398
- 6.Ranjbaran, Z., Keefer, L., Stepanski, E., Sedghi, S., & Keshavarzian, A. (2007). The relevance of sleep abnormalities to chronic inflammatory conditions. Inflammation Research, 56(2), 51-57. https://doi.org/10.1007/s00011-007-7374-9
- 7.Swanson, G. R., Burgess, H. J., & Keshavarzian, A. (2011). Sleep disturbances and inflammatory bowel disease: a potential trigger for disease flare? Expert Review of Clinical Immunology, 7(1), 29-36. https://doi.org/10.1586/eci.11.24
- 8.Trauer, J. M., Qian, M. Y., Doyle, J. S., Rajaratnam, S. M., & Cunnington, D. (2015). Cognitive behavioral therapy for chronic insomnia: a systematic review and meta-analysis. Annals of Internal Medicine, 163(3), 191-204. https://doi.org/10.7326/M14-2841
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247 Health News Editorial
247 Health News is a medical intelligence platform delivering evidence-based research appraisals, clinical trial monitoring, and health technology news for healthcare professionals.
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