Health Technology/clinical-trials

Pilot Trial Opens: Adaptive Mobile Health Intervention Targets Medication Adherence in Adolescents and Young Adults With Chronic Conditions — Design and Clinical Implications

247 Health News Editorial

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22 July 2026

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4 min read

·clinical-trials

Children's Hospital Los Angeles has opened a feasibility pilot trial testing an adaptive smartphone-based intervention to improve daily medication adherence in adolescents and young adults aged 15–20 with chronic health conditions. The study will assess acceptability, usability, and preliminary adherence outcomes across 35 participants ahead of a planned randomised controlled trial.

Originally reported by ClinicalTrials.gov

References

  1. 1.Children's Hospital Los Angeles. (2025). Adaptive cell phone support to promote medication adherence among adolescents and young adults with chronic health conditions (NCT07084155). ClinicalTrials.gov. https://clinicaltrials.gov/study/NCT07084155
  2. 2.Badawy, S. M., & Kuhns, L. M. (2017). Texting and mobile phone app interventions for improving adherence to preventive behavior in adolescents: A systematic review. JMIR mHealth and uHealth, 5(4), e50. https://doi.org/10.2196/mhealth.6837
  3. 3.Ingerski, L. M., Hente, E. A., Modi, A. C., & Hommel, K. A. (2011). Electronic measurement of medication adherence in pediatric chronic illness: A review of measures. Journal of Pediatrics, 159(4), 528–534. https://doi.org/10.1016/j.jpeds.2011.02.017
  4. 4.Thabane, L., Ma, J., Chu, R., Cheng, J., Ismaila, A., Rios, L. P., Robson, R., Thabane, M., Giangregorio, L., & Goldsmith, C. H. (2010). A tutorial on pilot studies: The what, why and how. BMC Medical Research Methodology, 10(1), 1. https://doi.org/10.1186/1471-2288-10-1
  5. 5.Pai, A. L. H., & Drotar, D. (2010). Treatment adherence in adolescents and young adults with chronic health conditions. Journal of Developmental and Behavioral Pediatrics, 31(6), 521–528. https://doi.org/10.1097/DBP.0b013e3181e21b1d
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