Health Technology/clinical-trials

Pilot Trial Explores Physical Activity Intervention for Chemo-Brain in Cancer Survivors With and Without Type 2 Diabetes

247 Health News Editorial

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9 May 2026

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4 min read

·clinical-trials

New pilot study investigates whether physical activity can improve cognitive function and brain blood flow in cancer survivors experiencing chemo-brain, with particular focus on those with type 2 diabetes. The 12-week technology-delivered intervention targets shared inflammatory pathways underlying both conditions.

Originally reported by ClinicalTrials.gov

References

  1. 1.University of Oklahoma. (2024). Cerebrovascular, Cognitive, Pro-Inflammatory, and Cardiometabolic Outcomes in Cancer Survivors With and Without Type II Diabetes Reporting Chemo-Brain: Baseline Differences and Impact of Activity. ClinicalTrials.gov. NCT06725953. https://clinicaltrials.gov/study/NCT06725953
  2. 2.Janelsins, M. C., Kesler, S. R., Ahles, T. A., & Morrow, G. R. (2014). Prevalence, mechanisms, and management of cancer-related cognitive impairment. International Review of Psychiatry, 26(1), 102-113. https://doi.org/10.3109/09540261.2014.864773
  3. 3.Kessels, R. P., Schagen, S. B., & Bruijn, M. A. (2022). Physical exercise and cognitive function in cancer survivors: A systematic review. Psycho-Oncology, 31(3), 412-428. https://doi.org/10.1002/pon.5845
  4. 4.Ahles, T. A., & Root, J. C. (2018). Cognitive effects of cancer and cancer treatments. Annual Review of Clinical Psychology, 14, 425-451. https://doi.org/10.1146/annurev-clinpsy-050817-084903
  5. 5.Miller, K. D., Nogueira, L., Devasia, T., Mariotto, A. B., Yabroff, K. R., Jemal, A., Kramer, J., & Siegel, R. L. (2022). Cancer treatment and survivorship statistics, 2022. CA: A Cancer Journal for Clinicians, 72(5), 409-436. https://doi.org/10.3322/caac.21731
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