Phase IV Validation Trial: AI-Based Modified Rankin Scale Scoring vs Manual Assessment in Stroke Patients — Clinical Performance Study
247 Health News Editorial
·24 Apr 2026
·4 min read
·clinical-trialsA new validation study examines AI-based Modified Rankin Scale scoring versus manual assessment in stroke patients. This research could standardise functional outcome measurement and reduce inter-rater variability in stroke care.
Originally reported by ClinicalTrials.gov
References
- 1.Australian Institute of Health and Welfare. (2023). Stroke in Australia. AIHW. https://www.aihw.gov.au/reports/heart-stroke-vascular-diseases/stroke
- 2.Banks, J. L., & Marotta, C. A. (2007). Outcomes validity and reliability of the modified Rankin scale: implications for stroke clinical trials. Stroke, 38(5), 1091-1096. https://doi.org/10.1161/01.STR.0000258355.23810.c6
- 3.Liu, X., Faes, L., Kale, A. U., Wagner, S. K., Fu, D. J., Bruynseels, A., ... & Denniston, A. K. (2019). A comparison of deep learning performance against health-care professionals in detecting diseases from medical imaging: a systematic review and meta-analysis. The Lancet Digital Health, 1(6), e271-e297. https://doi.org/10.1016/S2589-7500(19)30123-2
- 4.Rankin, J. (1957). Cerebral vascular accidents in patients over the age of 60. II. Prognosis. Scottish Medical Journal, 2(5), 200-215. https://doi.org/10.1177/003693305700200504
- 5.Wilson, J. T., Hareendran, A., Hendry, A., Potter, J., Bone, I., & Muir, K. W. (2005). Reliability of the modified Rankin Scale across multiple raters: benefits of a structured interview. Stroke, 36(4), 777-781. https://doi.org/10.1161/01.STR.0000177023.58609.f0
- 6.Xuanwu Hospital, Beijing. (2024). Clinical Validation of an Artificial Intelligence-Based Scoring System for the Modified Rankin Scale (mRS) in Patients With Stroke. ClinicalTrials.gov. https://clinicaltrials.gov/study/NCT07544927
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