Phase IV Trial Opens: Orpyx Smart Insoles vs Standard Care for Diabetic Foot Ulcer Prevention — What Clinicians Need to Know
247 Health News Editorial
·26 May 2026
·4 min read
·clinical-trialsNew multisite trial tests smart insole technology for preventing diabetic foot ulcer recurrence in high-risk patients. The Orpyx Sensory Insole System provides real-time pressure monitoring and feedback, potentially transforming diabetic foot care from reactive to proactive prevention.
Originally reported by ClinicalTrials.gov
References
- 1.Orpyx Medical Technologies Inc. (2023). Prevention of Foot Ulcer Recurrence in Individuals Who Are at High-risk for Diabetic Foot Complications Using the Orpyx Sensory Insole System. ClinicalTrials.gov. NCT05950659. https://clinicaltrials.gov/study/NCT05950659
- 2.Najafi, B., Mohseni, H., Grewal, G. S., Talal, T. K., Menzies, R. A., & Lavery, L. A. (2017). An optical-fiber-based smart textile (smart socks) to manage biomechanical risk factors associated with diabetic foot amputation. Journal of Diabetes Science and Technology, 11(4), 668-677. https://doi.org/10.1177/1932296817695338
- 3.Armstrong, D. G., Boulton, A. J., & Bus, S. A. (2017). Diabetic foot ulcers and their recurrence. New England Journal of Medicine, 376(24), 2367-2375. https://doi.org/10.1056/NEJMra1615439
- 4.Bus, S. A., Lavery, L. A., Monteiro‐Soares, M., Rasmussen, A., Raspovic, A., Sacco, I. C., & van Netten, J. J. (2020). Guidelines on the prevention of foot ulcers in persons with diabetes (IWGDF 2019 update). Diabetes/Metabolism Research and Reviews, 36(1), e3269. https://doi.org/10.1002/dmrr.3269
- 5.Kerr, M., Barron, E., Chadwick, P., Evans, T., Kong, W. M., Rayman, G., & Jeffcoate, W. J. (2019). The cost of diabetic foot ulcers and amputations to the National Health Service in England. Diabetic Medicine, 36(8), 995-1002. https://doi.org/10.1111/dme.13973
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247 Health News Editorial
247 Health News is a medical intelligence platform delivering evidence-based research appraisals, clinical trial monitoring, and health technology news for healthcare professionals.
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