Phase IV Trial Opens: Connected Platform vs Enhanced Care for CDK4/6 Inhibitor Adherence in Metastatic Breast Cancer — What Oncologists Need to Know
247 Health News Editorial
·5 Apr 2026
·4 min read
·clinical-trialsNew trial tests connected platform with text reminders versus standard monitoring to improve CDK4/6 inhibitor adherence in metastatic breast cancer. Results could transform routine oncology practice by 2027.
Originally reported by ClinicalTrials.gov
References
- 1.ECOG-ACRIN Cancer Research Group. (2023). Improving Medication Adherence in Metastatic Breast Cancer Using a Connected Customized Treatment Platform (CONCURxP). ClinicalTrials.gov. https://clinicaltrials.gov/study/NCT06112613
- 2.Finn, R. S., Martin, M., Rugo, H. S., Jones, S., Im, S. A., Gelmon, K., Harbeck, N., Lipatov, O. N., Walshe, J. M., Moulder, S., Gauthier, E., Lu, D. R., Randolph, S., Diéras, V., & Slamon, D. J. (2016). Palbociclib and letrozole in advanced breast cancer. New England Journal of Medicine, 375(20), 1925-1936. https://doi.org/10.1056/NEJMoa1607303
- 3.Greer, J. A., Amoyal, N., Nisotel, L., Fishbein, J. N., MacDonald, J., Stagl, J., Lennes, I., Temel, J. S., Safren, S. A., & Pirl, W. F. (2016). A systematic review of adherence to oral antineoplastic therapies. The Oncologist, 21(12), 1511-1519. https://doi.org/10.1634/theoncologist.2015-0405
- 4.Spoelstra, S. L., Given, B. A., Given, C. W., Grant, M., Sikorskii, A., You, M., & Decker, V. (2013). An intervention to improve adherence and management of symptoms for patients prescribed oral chemotherapy agents. Cancer Nursing, 36(1), 18-28. https://doi.org/10.1097/NCC.0b013e31826fcdc2
- 5.Hershman, D. L., Kushi, L. H., Shao, T., Buono, D., Kershenbaum, A., Tsai, W. Y., Fehrenbacher, L., Lin Gomez, S., Miles, S., & Neugut, A. I. (2010). Early discontinuation and nonadherence to adjuvant hormonal therapy in a cohort of 8,769 early-stage breast cancer patients. Journal of Clinical Oncology, 28(27), 4120-4128. https://doi.org/10.1200/JCO.2009.25.9655
2
247 Health News Editorial
247 Health News is a medical intelligence platform delivering evidence-based research appraisals, clinical trial monitoring, and health technology news for healthcare professionals.
Related Articles
clinical-trials
Digital Health Platform vs Case Manager Support in Hypertension Management: Taiwan's 1,726-Participant Trial Signals a Shift in Blood Pressure Care Delivery
3 Aug 2026
clinical-trials
Phase II Trial: AI-Powered Wysa Chatbot vs Unmet Need — Digital Eating Disorder Prevention in At-Risk Adolescents
3 Aug 2026
clinical-trials
Pilot Trial Targets the Inpatient-to-Outpatient Gap: Digital Smoking Cessation Intervention for Persons With Serious Mental Illness — Key Findings for Clinicians
3 Aug 2026
This content is for educational purposes for healthcare professionals only and does not constitute clinical advice. Clinical decisions should be based on individual patient assessment, current guidelines, and appropriate specialist consultation. Editorial Standards · Privacy Policy · Terms of Service