Phase IV Trial Opens: Awake Mastectomy Day Surgery vs Standard Care in Breast Reconstruction — What Clinicians Need to Know
247 Health News Editorial
·5 Apr 2026
·3 min read
·clinical-trialsItalian researchers are testing whether awake mastectomy with same-day discharge can match traditional inpatient care for safety and pain control in breast reconstruction. The AMADeuS trial could revolutionise breast cancer surgery delivery.
Originally reported by ClinicalTrials.gov
References
- 1.University of Rome Tor Vergata. (2024). Evaluation of Safety, Quality of Life, Cost and Environmental Impact of Day Surgery in Mastectomy and Prepectoral Reconstruction. ClinicalTrials.gov. NCT07510698. https://clinicaltrials.gov/study/NCT07510698
- 2.Ljungqvist, O., Scott, M., & Fearon, K. C. (2017). Enhanced recovery after surgery: a review. JAMA Surgery, 152(3), 292-298. https://doi.org/10.1001/jamasurg.2017.0952
- 3.Batdorf, N. J., Lemaine, V., & Lovely, J. K. (2015). Enhanced recovery after surgery in microvascular breast reconstruction. Journal of Plastic, Reconstructive & Aesthetic Surgery, 68(3), 395-402. https://doi.org/10.1016/j.bjps.2015.06.007
- 4.Sigalove, S., Maxwell, G. P., Sigalove, N. M., Storm-Dickerson, T. L., Pope, N., Rice, J., & Gabriel, A. (2017). Prepectoral implant-based breast reconstruction: rationale, indications, and preliminary results. Plastic and Reconstructive Surgery, 139(2), 287-294. https://doi.org/10.1097/PRS.0000000000003627
- 5.Australian Institute of Health and Welfare. (2023). Cancer in Australia 2023. AIHW. https://www.aihw.gov.au/reports/cancer/cancer-in-australia-2023
- 6.Temple-Oberle, C., Shea-Budgell, M. A., Tan, M., Semple, J. L., Schrag, C., Barreto, M., ... & Doherty, C. (2017). Consensus review of optimal perioperative care in breast reconstruction. Plastic and Reconstructive Surgery, 139(5), 1056e-1071e. https://doi.org/10.1097/PRS.0000000000003242
- 7.Malik, A., Lenzen-Schulte, M., Amann, J., & Rohde, N. (2018). The carbon footprint of Australian health care. The Lancet Planetary Health, 2(1), e27-e35. https://doi.org/10.1016/S2542-5196(18)30204-5
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247 Health News Editorial
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