Phase IV Trial Opens: AI-Powered Consent Tool vs Traditional Methods in Anaesthesia — Singapore Study Targets Patient Understanding
247 Health News Editorial
·13 May 2026
·4 min read
·clinical-trialsSingapore General Hospital launches groundbreaking trial comparing AI-powered PEAR chatbot against traditional anaesthesia consent methods. The study evaluates whether multilingual AI can improve patient understanding of anaesthetic risks across diverse populations.
Originally reported by ClinicalTrials.gov
References
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- 2.Fink, A. S., Prochazka, A. V., Henderson, W. G., Bartenfelder, D., Nyirenda, C., Webb, A., ... & Parmelee, P. (2010). Enhancement of surgical informed consent by addition of repeat back: a multicenter, randomized controlled clinical trial. Annals of Surgery, 252(1), 27-36. https://doi.org/10.1097/SLA.0b013e3181e3ec61
- 3.Jlala, H. A., French, J. L., Foxall, G. L., Hardman, J. G., & Bedforth, N. M. (2010). Effect of preoperative multimedia information on perioperative anxiety in patients undergoing procedures under regional anaesthesia. British Journal of Anaesthesia, 104(3), 369-374. https://doi.org/10.1093/bja/aeq002
- 4.Keulers, B. J., Welters, C. F., Spauwen, P. H., & Houpt, P. (2007). Can face-to-face patient education be replaced by computer-based patient education? A randomised trial. Patient Education and Counseling, 67(1-2), 176-182. https://doi.org/10.1016/j.pec.2006.04.004
- 5.Kinnersley, P., Phillips, K., Savage, K., Kelly, M. J., Farrell, E., Morgan, B., ... & Edwards, A. (2013). Interventions to promote informed consent for patients undergoing surgical and other invasive healthcare procedures. Cochrane Database of Systematic Reviews, (7). https://doi.org/10.1002/14651858.CD009445.pub3
- 6.Schenker, Y., Fernandez, A., Sudore, R., & Schillinger, D. (2011). Interventions to improve patient comprehension in informed consent for medical and surgical procedures: a systematic review. Medical Decision Making, 31(1), 151-173. https://doi.org/10.1177/0272989X10364247
- 7.Singapore General Hospital. (2024). Evaluating the Effectiveness of Large Language Models in Anaesthesia and Procedural Consent: A Comparative Analysis With Traditional Patient Consent Methods. ClinicalTrials.gov. NCT06949462. https://clinicaltrials.gov/study/NCT06949462
- 8.Tam, N. T., Huy, N. T., Thoa, L. T. B., Long, N. P., Trang, N. T. H., Hirayama, K., & Karbwang, J. (2015). Participants' understanding of informed consent in clinical trials over three decades: systematic review and meta-analysis. Bulletin of the World Health Organization, 93(3), 186-198H. https://doi.org/10.2471/BLT.14.141390
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