Health Technology/clinical-trials

Phase IV Trial Opens: AI-Enhanced Point-of-Care Cardiac Ultrasound vs Complete Echocardiography in Paediatric Cardiac Disease — What Emergency and Cardiology Clinicians Need to Know

247 Health News Editorial

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4 Apr 2026

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4 min read

·clinical-trials

New US trial evaluates AI-enhanced point-of-care cardiac ultrasound performed by emergency medicine fellows against formal echocardiography in children with preexisting cardiac disease. Results could transform bedside cardiac assessment in paediatric emergency departments worldwide.

Originally reported by ClinicalTrials.gov

References

  1. 1.Cantinotti, M., Giordano, R., Koestenberger, M., Marchese, P., Franchi, E., Assanta, N., ... & Crocetti, M. (2021). Echocardiography for congenital heart disease diagnosis in newborns: a position paper by the European Association of Cardiovascular Imaging. European Heart Journal Cardiovascular Imaging, 22(11), 1284-1295. https://doi.org/10.1093/ehjci/jeab151
  2. 2.Karsenty, C., Maury, P., Blot-Souletie, N., Ladouceur, M., Leobon, B., Senac, V., ... & Acar, P. (2020). The medical history of adults with complex congenital heart disease affects their social development and professional activity. Archives of Cardiovascular Diseases, 113(2), 89-98. https://doi.org/10.1016/j.acvd.2019.11.009
  3. 3.Longjohn, M., Wan, J., Joshi, V., & Pershad, J. (2021). Point-of-care echocardiography by pediatric emergency physicians. Pediatric Emergency Care, 37(1), e1-e6. https://doi.org/10.1097/PEC.0000000000002043
  4. 4.Narasimhan, M., Koenig, S. J., & Mayo, P. H. (2014). Advanced echocardiography for the critical care physician: part 1. Chest, 145(1), 129-134. https://doi.org/10.1378/chest.13-2441
  5. 5.Nicklaus Children's Hospital. (2024). Prospective Evaluation of Cardiac Point-of-Care Ultrasound (POCUS) Performed by PEM Fellows and Artificial Intelligence Interpretation Compared With a Complete Echocardiography in Children With Preexisting Cardiac Disease. ClinicalTrials.gov. NCT07503158. https://clinicaltrials.gov/study/NCT07503158
  6. 6.Ouyang, D., He, B., Ghorbani, A., Yuan, N., Ebinger, J., Langlotz, C. P., ... & Zou, J. Y. (2020). Video-based AI for beat-to-beat assessment of cardiac function. Nature, 580(7802), 252-256. https://doi.org/10.1038/s41586-020-2145-8
  7. 7.Riera, A., Hsiao, A., Langhan, M., Goodman, T. R., & Chen, L. (2022). Diagnosis of acute heart failure in children: role of point-of-care ultrasound. Pediatric Emergency Care, 38(2), e654-e659. https://doi.org/10.1097/PEC.0000000000002575
  8. 8.Singh, Y., Tissot, C., Fraga, M. V., Yousef, N., Cortes, R. G., Lopez, J., ... & El-Khuffash, A. (2020). International evidence-based guidelines for point of care lung ultrasound. Intensive Care Medicine, 46(6), 1084-1106. https://doi.org/10.1007/s00134-020-06048-9
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247 Health News Editorial

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