Phase III Trial Tests Digital Contingency Management App for Polysubstance Use in Methadone Patients — Novel Approach to Retention and Abstinence
247 Health News Editorial
·29 May 2026
·3 min read
·clinical-trialsA phase III trial tests DynamiCare Health, a smartphone app using remote drug testing and financial incentives, as an add-on to methadone maintenance therapy for patients with concurrent opioid and cocaine use disorders. The study aims to improve 48-week retention rates and reduce polysubstance use through digital contingency management.
Originally reported by ClinicalTrials.gov
References
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- 2.Dallery, J., Jarvis, B., Marsch, L., & Xie, H. (2015). Mechanisms of change associated with technology-based interventions for substance use. Drug and Alcohol Dependence, 150, 14-23. https://doi.org/10.1016/j.drugalcdep.2015.01.036
- 3.Friends Research Institute. (2024). Treating Polysubstance Use in Methadone Maintenance: Application of Novel Digital Technology. ClinicalTrials.gov. https://clinicaltrials.gov/study/NCT05766631
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- 5.Luo, S. X., Coventry, W. L., Agrawal, A., Lynskey, M., Madden, P. A., Bucholz, K. K., ... & Nelson, E. C. (2018). Associations of substance use disorders with clinical and demographic characteristics in a large cohort. Journal of Psychiatric Research, 103, 133-141. https://doi.org/10.1016/j.jpsychires.2018.04.012
- 6.Marsch, L. A., & Borodovsky, J. T. (2016). Technology-based interventions for preventing and treating substance use among youth. Child and Adolescent Psychiatric Clinics, 25(4), 755-768. https://doi.org/10.1016/j.chc.2015.11.003
- 7.Petry, N. M., & Martin, B. (2002). Low-cost contingency management for treating cocaine- and opioid-abusing methadone patients. Journal of Consulting and Clinical Psychology, 70(2), 398-405. https://doi.org/10.1037/0022-006X.70.2.398
- 8.Williamson, A., Darke, S., Ross, J., & Teesson, M. (2006). The association between cocaine use and short-term outcomes for the treatment of heroin dependence: Findings from the Australian Treatment Outcome Study (ATOS). Drug and Alcohol Review, 25(2), 141-148. https://doi.org/10.1080/09595230600944545
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247 Health News Editorial
247 Health News is a medical intelligence platform delivering evidence-based research appraisals, clinical trial monitoring, and health technology news for healthcare professionals.
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