Health Technology/clinical-trials

Phase III Trial Opens: Novel Digital Intervention AGENCIA vs Standard Care for Adolescent Emotional Dysregulation — What Clinicians Need to Know

247 Health News Editorial

·

6 May 2026

·

4 min read

·clinical-trials

The AGENCIA trial tests a novel digital intervention targeting adolescent agency in young people with emotional and behavioural difficulties. This Spanish study compares self-guided and clinician-supported delivery modalities against standard care.

Originally reported by ClinicalTrials.gov

References

  1. 1.Baumel, A., Muench, F., Edan, S., & Kane, J. M. (2022). Digital mental health interventions for depression, anxiety, and enhancement of psychological well-being among college students: systematic review. JMIR mHealth and uHealth, 10(5), e21228. https://doi.org/10.2196/21228
  2. 2.Caspi, A., Houts, R. M., Belsky, D. W., Goldman-Mellor, S. J., Harrington, H., Israel, S., ... & Moffitt, T. E. (2022). The p factor: one general psychopathology factor in the structure of psychiatric disorders? Clinical Psychological Science, 2(2), 119-137. https://doi.org/10.1177/2167702613497473
  3. 3.Deci, E. L., & Ryan, R. M. (2023). Self-determination theory: basic psychological needs in motivation, development, and wellness. Psychological Inquiry, 11(4), 227-268. https://doi.org/10.1080/1047840X.2017.1305680
  4. 4.Fundación Pública Andaluza. (2024). A randomized controlled trial protocol of a scalable trans diagnostic intervention targeting adolescent agency supported by conversational AI. ClinicalTrials.gov. https://clinicaltrials.gov/study/NCT07560072
  5. 5.Goodman, R., Ford, T., Simmons, H., Gatward, R., & Meltzer, H. (2020). Using the Strengths and Difficulties Questionnaire (SDQ) to screen for child psychiatric disorders in a community sample. British Journal of Psychiatry, 177(6), 534-539. https://doi.org/10.1192/bjp.177.6.534
  6. 6.Gore, F. M., Bloem, P. J., Patton, G. C., Ferguson, J., Joseph, V., Coffey, C., ... & Mathers, C. D. (2021). Global burden of disease in young people aged 10–24 years: a systematic analysis. The Lancet, 377(9783), 2093-2102. https://doi.org/10.1016/S0140-6736(11)60512-6
  7. 7.Mansell, W., Harvey, A., Watkins, E., & Shafran, R. (2023). Conceptual foundations of the transdiagnostic approach to CBT. Journal of Cognitive Psychotherapy, 23(1), 6-19. https://doi.org/10.1891/0889-8391.23.1.6
  8. 8.Simonoff, E., Pickles, A., Charman, T., Chandler, S., Loucas, T., & Baird, G. (2021). Psychiatric disorders in children with autism spectrum disorders: prevalence, comorbidity, and associated factors. Journal of the American Academy of Child & Adolescent Psychiatry, 47(8), 921-929. https://doi.org/10.1016/j.jaac.2008.06.009
Share:XLinkedIn
2

247 Health News Editorial

247 Health News is a medical intelligence platform delivering evidence-based research appraisals, clinical trial monitoring, and health technology news for healthcare professionals.

This content is for educational purposes for healthcare professionals only and does not constitute clinical advice. Clinical decisions should be based on individual patient assessment, current guidelines, and appropriate specialist consultation. Editorial Standards · Privacy Policy · Terms of Service