Health Technology/clinical-trials

Phase III Trial Opens: mHealth Screening vs Conventional Methods for Oral Cancer Detection in High-Risk Populations — What Clinicians Need to Know

247 Health News Editorial

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7 June 2026

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3 min read

·clinical-trials

A major prospective trial is comparing mobile health technology against conventional screening for oral cancer detection in high-risk rural populations. The 5,122-participant study could transform access to oral cancer screening in resource-limited settings.

Originally reported by ClinicalTrials.gov

References

  1. 1.Gupta, B., & Johnson, N. W. (2014). Systematic review and meta-analysis of association of smokeless tobacco and of betel quid without tobacco with incidence of oral cancer in South Asia and the Pacific. PLoS One, 9(11), e113385. https://doi.org/10.1371/journal.pone.0113385
  2. 2.Johnson, N. W., Jayasekara, P., & Amarasinghe, A. A. (2011). Squamous cell carcinoma and precursor lesions of the oral cavity: epidemiology and aetiology. Periodontology 2000, 57(1), 19-37. https://doi.org/10.1111/j.1600-0757.2011.00401.x
  3. 3.Memorial Sloan Kettering Cancer Center. (2024). The Efficacy of Conventional Screening Versus mHealth Screening in Early Detection of Oral Potentially Malignant Disorders and Oral Cancer Amongst the Rural Population of Varanasi: A Prospective and Blinded Study. ClinicalTrials.gov. NCT06535867. https://clinicaltrials.gov/study/NCT06535867
  4. 4.Sung, H., Ferlay, J., Siegel, R. L., Laversanne, M., Soerjomataram, I., Jemal, A., & Bray, F. (2021). Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA: A Cancer Journal for Clinicians, 71(3), 209-249. https://doi.org/10.3322/caac.21660
  5. 5.Warnakulasuriya, S., Kujan, O., Aguirre-Urizar, J. M., Bagan, J. V., González-Moles, M. Á., Kerr, A. R., ... & Scully, C. (2021). Oral potentially malignant disorders: A consensus report from an international seminar on nomenclature and classification. Oral Diseases, 27(8), 1862-1880. https://doi.org/10.1111/odi.13704
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247 Health News Editorial

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