Phase III Trial Opens: Digital Symptom Monitoring App vs Standard Care in Cancer — What Clinicians Need to Know
247 Health News Editorial
·5 Apr 2026
·4 min read
·clinical-trialsThe RC-102 Phase III trial is testing whether a smartphone app for symptom monitoring can improve quality of life in cancer patients. With 1,458 participants across Europe, this study could reshape how oncologists monitor treatment-related symptoms between clinic visits.
Originally reported by ClinicalTrials.gov
References
- 1.Absolom, K., Warrington, L., Hudson, E., Hewison, J., Morris, C., Holch, P., Carter, R., Gibson, A., Hinsley, S., Velikova, G., & eRAPID Trial Management Group. (2021). Phase III randomized controlled trial of eRAPID: eHealth intervention during chemotherapy. Journal of Clinical Oncology, 39(7), 734-747. https://doi.org/10.1200/JCO.20.02015
- 2.Basch, E., Deal, A. M., Dueck, A. C., Scher, H. I., Kris, M. G., Hudis, C., & Schrag, D. (2017). Overall survival results of a trial assessing patient-reported outcomes for symptom monitoring during routine cancer treatment. JAMA, 318(2), 197-198. https://doi.org/10.1001/jama.2017.7156
- 3.Basch, E., Deal, A. M., Kris, M. G., Scher, H. I., Hudis, C. A., Sabbatini, P., Rogak, L., Bennett, A. V., Dueck, A. C., Atkinson, T. M., Chou, J. F., Dulko, D., Sit, L., Balk, E. M., Rogak, L., Cycowitz, K., Zipkin, D., & Schrag, D. (2016). Symptom monitoring with patient-reported outcomes during routine cancer treatment: a randomized controlled trial. Journal of Clinical Oncology, 34(6), 557-565. https://doi.org/10.1200/JCO.2015.63.0830
- 4.Denis, F., Basch, E., Septans, A. L., Bennouna, J., Urban, T., Dueck, A. C., & Letellier, C. (2019). Two-year survival comparing web-based symptom monitoring vs routine surveillance following treatment for lung cancer. JAMA, 321(3), 306-307. https://doi.org/10.1001/jama.2018.18085
- 5.Kotronoulas, G., Kearney, N., Maguire, R., Harrow, A., Di Domenico, D., Croy, S., & MacGillivray, S. (2014). What is the value of the routine use of patient-reported outcome measures toward improvement of patient outcomes, processes of care, and health service outcomes in cancer care? Journal of Clinical Oncology, 32(14), 1480-1501. https://doi.org/10.1200/JCO.2013.53.5948
- 6.Resilience. (2024). Digital Monitoring With Patient-Reported Outcomes in Cancer Care: A Randomized Controlled Trial RC - 102 (Resilience Care - 102). ClinicalTrials.gov. NCT06867705. https://clinicaltrials.gov/study/NCT06867705
- 7.Ruland, C. M., Holte, H. H., Røislien, J., Heaven, C., Hamilton, G. A., Kristiansen, J., Sandbaek, H., Kvaløy, S. O., Hasund, M., Ellison, M. C., & Andersen, T. (2010). Effects of a computer-supported system to monitor symptoms and communicate with healthcare providers on quality of life in cancer patients. Journal of the American Medical Informatics Association, 17(2), 161-168. https://doi.org/10.1136/jamia.2009.002022
- 8.Sedhom, R., Gupta, A., Kopetz, S., Jabbour, S. K., Malin, J. L., & Manne, S. (2022). Mobile health applications in oncology: a systematic review of health care interventions and outcomes. JMIR mHealth and uHealth, 10(3), e35543. https://doi.org/10.2196/35543
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247 Health News Editorial
247 Health News is a medical intelligence platform delivering evidence-based research appraisals, clinical trial monitoring, and health technology news for healthcare professionals.
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