Health Technology/clinical-trials

Phase III Trial Opens: Continuous Glucose Monitoring-Based Lifestyle Program vs Standard Care in Early Type 2 Diabetes — What Clinicians Need to Know

247 Health News Editorial

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12 Apr 2026

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4 min read

·clinical-trials

A groundbreaking trial is testing whether continuous glucose monitoring combined with personalized lifestyle coaching can improve outcomes in newly diagnosed type 2 diabetes patients while reducing medication requirements. The TREATING study could reshape early diabetes management approaches.

Originally reported by ClinicalTrials.gov

References

  1. 1.Fabris, C. (2023). Treating Early Type 2 Diabetes by Reducing Postprandial Glucose Excursions: A Paradigm Shift in Lifestyle Modification. ClinicalTrials.gov. NCT05766735. https://clinicaltrials.gov/study/NCT05766735
  2. 2.Davies, M. J., Aroda, V. R., Collins, B. S., Gabbay, R. A., Green, J., Maruthur, N. M., Rosas, S. E., Del Prato, S., Mathieu, C., Mingrone, G., Rossing, P., Tankova, T., Tsapas, A., & Buse, J. B. (2022). Management of hyperglycemia in type 2 diabetes, 2022. A consensus report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD). Diabetes Care, 45(11), 2753-2786. https://doi.org/10.2337/dci22-0034
  3. 3.Beck, R. W., Riddlesworth, T., Ruedy, K., Ahmann, A., Bergenstal, R., Haller, S., Kollman, C., Kruger, D., McGill, J. B., Polonsky, W., Toschi, E., Wolpert, H., & Price, D. (2017). Effect of continuous glucose monitoring on glycemic control in adults with type 1 diabetes. JAMA, 317(4), 371-378. https://doi.org/10.1001/jama.2017.10833
  4. 4.Monnier, L., Mas, E., Ginet, C., Michel, F., Villon, L., Cristol, J. P., & Colette, C. (2006). Activation of oxidative stress by acute glucose fluctuations compared with sustained chronic hyperglycemia in patients with type 2 diabetes. JAMA, 295(14), 1681-1687. https://doi.org/10.1001/jama.295.14.1681
  5. 5.Magliano, D. J., Sacre, J. W., Harding, J. L., Gregg, E. W., Zimmet, P. Z., & Shaw, J. E. (2020). Young-onset type 2 diabetes mellitus — implications for morbidity and mortality. Nature Reviews Endocrinology, 16(6), 321-331. https://doi.org/10.1038/s41574-020-0334-z
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