Phase III Trial Opens: Continuous Glucose Monitoring-Based Lifestyle Program vs Standard Care in Early Type 2 Diabetes — What Clinicians Need to Know
247 Health News Editorial
·12 Apr 2026
·4 min read
·clinical-trialsA groundbreaking trial is testing whether continuous glucose monitoring combined with personalized lifestyle coaching can improve outcomes in newly diagnosed type 2 diabetes patients while reducing medication requirements. The TREATING study could reshape early diabetes management approaches.
Originally reported by ClinicalTrials.gov
References
- 1.Fabris, C. (2023). Treating Early Type 2 Diabetes by Reducing Postprandial Glucose Excursions: A Paradigm Shift in Lifestyle Modification. ClinicalTrials.gov. NCT05766735. https://clinicaltrials.gov/study/NCT05766735
- 2.Davies, M. J., Aroda, V. R., Collins, B. S., Gabbay, R. A., Green, J., Maruthur, N. M., Rosas, S. E., Del Prato, S., Mathieu, C., Mingrone, G., Rossing, P., Tankova, T., Tsapas, A., & Buse, J. B. (2022). Management of hyperglycemia in type 2 diabetes, 2022. A consensus report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD). Diabetes Care, 45(11), 2753-2786. https://doi.org/10.2337/dci22-0034
- 3.Beck, R. W., Riddlesworth, T., Ruedy, K., Ahmann, A., Bergenstal, R., Haller, S., Kollman, C., Kruger, D., McGill, J. B., Polonsky, W., Toschi, E., Wolpert, H., & Price, D. (2017). Effect of continuous glucose monitoring on glycemic control in adults with type 1 diabetes. JAMA, 317(4), 371-378. https://doi.org/10.1001/jama.2017.10833
- 4.Monnier, L., Mas, E., Ginet, C., Michel, F., Villon, L., Cristol, J. P., & Colette, C. (2006). Activation of oxidative stress by acute glucose fluctuations compared with sustained chronic hyperglycemia in patients with type 2 diabetes. JAMA, 295(14), 1681-1687. https://doi.org/10.1001/jama.295.14.1681
- 5.Magliano, D. J., Sacre, J. W., Harding, J. L., Gregg, E. W., Zimmet, P. Z., & Shaw, J. E. (2020). Young-onset type 2 diabetes mellitus — implications for morbidity and mortality. Nature Reviews Endocrinology, 16(6), 321-331. https://doi.org/10.1038/s41574-020-0334-z
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