Health Technology/clinical-trials

Phase III Trial Opens: AI-Enhanced Ultrasound System vs Standard Protocol in First-Trimester Screening — What Clinicians Need to Know

247 Health News Editorial

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31 May 2026

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3 min read

·clinical-trials

New multicentre trial validates AI-enhanced ultrasound system for first-trimester screening, comparing automated image guidance against standard protocols in 1,000 pregnancies. Results could transform prenatal screening efficiency and accuracy.

Originally reported by ClinicalTrials.gov

References

  1. 1.Burgos-Artizzu, X. P., Coronado-Gutiérrez, D., Valenzuela-Alcaraz, B., Vellvé, K., Eixarch, E., Crispi, F., & Gratacós, E. (2020). Evaluation of deep convolutional neural networks for automatic classification of common maternal fetal ultrasound planes. Scientific Reports, 10(1), 10200. https://doi.org/10.1038/s41598-020-67076-5
  2. 2.Drukker, L., Noble, J. A., & Papageorghiou, A. T. (2020). Introduction to artificial intelligence in ultrasound imaging in obstetrics and gynecology. Ultrasound in Obstetrics & Gynecology, 56(4), 498-505. https://doi.org/10.1002/uog.22122
  3. 3.Nicolaides, K. H. (2023). Screening for fetal aneuploidies at 11 to 13 weeks. Prenatal Diagnosis, 43(4), 457-465. https://doi.org/10.1002/pd.6308
  4. 4.Poon, L. C., Tan, M. Y., Yerlikaya, G., Syngelaki, A., & Nicolaides, K. H. (2012). Birth weight in live births and stillbirths. Ultrasound in Obstetrics & Gynecology, 40(5), 523-530. https://doi.org/10.1002/uog.11110
  5. 5.Salomon, L. J., Alfirevic, Z., Berghella, V., Bilardo, C., Hernandez-Andrade, E., Johnsen, S. L., Kalache, K., Leung, K. Y., Malinger, G., Munoz, H., Prefumo, F., Toi, A., & Lee, W. (2022). ISUOG Practice Guidelines: ultrasound assessment of fetal biometry and growth. Ultrasound in Obstetrics & Gynecology, 59(4), 503-515. https://doi.org/10.1002/uog.24791
  6. 6.Union Hospital, Tongji Medical College, Huazhong University of Science and Technology. (2024). Validation of an AI-based intelligent image quality control system for first-trimester ultrasound scan: A stepwise, multicenter, randomized clinical trial in China. ClinicalTrials.gov. NCT07601191. https://clinicaltrials.gov/study/NCT07601191
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247 Health News Editorial

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