Health Technology/clinical-trials

Phase III Trial Opens: AI-Enhanced Narrative Writing vs Standard Approaches for Prolonged Grief in Chinese Adolescents — What Clinicians Need to Know

247 Health News Editorial

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22 May 2026

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4 min read

·clinical-trials

A groundbreaking trial in China tests whether AI-enhanced narrative writing can effectively treat prolonged grief in bereaved adolescents. The three-arm study compares AI-assisted therapy against standard approaches, potentially offering a scalable solution for adolescent grief intervention.

Originally reported by ClinicalTrials.gov

References

  1. 1.Melhem, N. M., Moritz, G., Walker, M., Shear, M. K., & Brent, D. (2007). Phenomenology and correlates of complicated grief in children and adolescents. Journal of the American Academy of Child & Adolescent Psychiatry, 46(4), 493-499. https://doi.org/10.1097/chi.0b013e31802e4070
  2. 2.Peking University. (2024). AI-Assisted Grief-Focused Guided Narrative Writing for Subclinical Prolonged Grief Disorder in Bereaved Chinese Adolescents: A Three-Arm Parallel Randomized Controlled Trial. ClinicalTrials.gov. NCT07589088. https://clinicaltrials.gov/study/NCT07589088
  3. 3.Prigerson, H. G., Boelen, P. A., Xu, J., Smith, K. V., & Maciejewski, P. K. (2021). Validation of the new DSM-5-TR criteria for prolonged grief disorder and the PG-13-Revised (PG-13-R) scale. Psychological Medicine, 52(14), 3363-3373. https://doi.org/10.1017/S0033291721001999
  4. 4.Rosner, R., Pfoh, G., Kotoučová, M., & Hagl, M. (2014). Efficacy of an outpatient treatment for prolonged grief disorder: a randomized controlled clinical trial. Journal of Affective Disorders, 167, 56-63. https://doi.org/10.1016/j.jad.2014.05.035
  5. 5.Smyth, J. M., Stone, A. A., Hurewitz, A., & Kaell, A. (1999). Effects of writing about stressful experiences on symptom reduction in patients with asthma or rheumatoid arthritis. JAMA, 281(14), 1304-1309. https://doi.org/10.1001/jama.281.14.1304
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247 Health News Editorial

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