Phase III Trial Opens: AI-Assisted Exercise vs Paper-Based Programs in Knee Osteoarthritis — Digital Health Innovation for Primary Care

References

1. 1.Australian Institute of Health and Welfare. (2023). Osteoarthritis in Australia (PHE 309). AIHW. https://www.aihw.gov.au/reports/arthritis-other-musculoskeletal-conditions/osteoarthritis-in-australia
2. 2.Bannuru, R. R., Osani, M. C., Vaysbrot, E. E., Arden, N. K., Bennell, K., Bierma-Zeinstra, S. M. A., Kraus, V. B., Lohmander, L. S., Abbott, J. H., Bhandari, M., Blanco, F. J., Espinosa, R., Haugen, I. K., Lin, J., Mandl, L. A., Moilanen, E., Nakamura, N., Snyder-Mackler, L., Trojian, T., ... McAlindon, T. E. (2019). OARSI guidelines for the non-surgical management of knee, hip, and polyarticular osteoarthritis. Osteoarthritis and Cartilage, 27(11), 1578-1589. https://doi.org/10.1016/j.joca.2019.06.011
3. 3.Dobson, F., Hinman, R. S., Roos, E. M., Abbott, J. H., Stratford, P., Davis, A. M., Buchbinder, R., Snyder-Mackler, L., Henrotin, Y., Thumboo, J., Hansen, P., & Bennell, K. L. (2013). OARSI recommended performance-based tests to assess physical function in people diagnosed with hip or knee osteoarthritis. Osteoarthritis and Cartilage, 21(8), 1042-1052. https://doi.org/10.1016/j.joca.2013.05.002
4. 4.Goh, S. L., Persson, M. S., Stocks, J., Hou, Y., Welton, N. J., Lin, J., Hall, M. C., Doherty, M., & Zhang, W. (2019). Efficacy and potential determinants of exercise therapy in knee and hip osteoarthritis: A systematic review and meta-analysis. Annals of Physical and Rehabilitation Medicine, 62(5), 356-365. https://doi.org/10.1016/j.rehab.2019.04.006
5. 5.Hunter, D. J., March, L., & Chew, M. (2020). Osteoarthritis in 2020 and beyond: a Lancet Commission. The Lancet, 396(10264), 1711-1712. https://doi.org/10.1016/S0140-6736(20)32230-3
6. 6.Kolasinski, S. L., Neogi, T., Hochberg, M. C., Oatis, C., Guyatt, G., Block, J., Callahan, L., Copenhaver, C., Dieppe, P., Dreiser, R. L., Eckstein, F., Felson, D. T., Gellar, K., Harvey, W. F., Hawker, G., Herzog, W., Hochberg, M. C., Hurley, M. V., Kwoh, C. K., ... Reston, J. (2020). 2019 American College of Rheumatology/Arthritis Foundation Guideline for the Management of Osteoarthritis of the Hand, Hip, and Knee. Arthritis & Rheumatism, 72(2), 220-233. https://doi.org/10.1002/art.41142
7. 7.Pisters, M. F., Veenhof, C., van Meeteren, N. L., Ostelo, R. W., de Bakker, D. H., Schellevis, F. G., & Dekker, J. (2007). Long-term effectiveness of exercise therapy in patients with osteoarthritis of the hip or knee: a systematic review. Arthritis & Rheumatism, 57(7), 1245-1253. https://doi.org/10.1002/art.22972
8. 8.Universidad Complutense de Madrid. (2024). Efficacy of Artificial Intelligence-Assisted Therapeutic Exercise in Patients With Knee Osteoarthritis: A Randomized Controlled Clinical Trial. ClinicalTrials.gov. https://clinicaltrials.gov/study/NCT07434011