Health Technology/clinical-trials

Phase III Trial Opens: AI-Assisted Colonoscopy vs Standard Screening — What Gastroenterologists Need to Know

247 Health News Editorial

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2 Apr 2026

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4 min read

·clinical-trials

Royal Melbourne Hospital launches Phase III trial comparing AI-assisted colonoscopy to standard screening for improved adenoma detection. The 1,200-patient study across Australia and UK aims to enhance colorectal cancer prevention through technology-augmented endoscopy.

Originally reported by ClinicalTrials.gov

References

  1. 1.Australian Institute of Health and Welfare. (2023). Cancer in Australia 2023 (CAN 144). AIHW. https://www.aihw.gov.au/reports/cancer/cancer-in-australia-2023
  2. 2.Corley, D. A., Jensen, C. D., Marks, A. R., Zhao, W. K., Lee, J. K., Doubeni, C. A., Zauber, A. G., de Boer, J., Fireman, B. H., Quesenberry, C. P., Quinn, V. P., Schottinger, J. E., Winawer, S. J., & Selby, J. V. (2014). Adenoma detection rate and risk of colorectal cancer and death. New England Journal of Medicine, 370(14), 1298-1306. https://doi.org/10.1056/NEJMoa1309086
  3. 3.Hassan, C., Antonelli, G., Dumonceau, J. M., Regula, J., Bretthauer, M., Chaussade, S., Dekker, E., Dinis-Ribeiro, M., Ferlitsch, M., Gimeno-García, A., Hazewinkel, Y., Jover, R., Kalager, M., Loberg, M., Pox, C., Rembacken, B., Rutter, M. D., Senore, C., Valori, M., ... Dufresne, L. (2019). Post-polypectomy colonoscopy surveillance: European Society of Gastrointestinal Endoscopy (ESGE) Guideline. Endoscopy, 51(3), 213-223. https://doi.org/10.1055/a-0865-4443
  4. 4.Rex, D. K., Schoenfeld, P. S., Cohen, J., Pike, I. M., Adler, D. G., Fennerty, M. B., Lieb, J. G., Park, W. G., Rizk, M. K., Sawhney, M. S., Shaheen, N. J., Wani, S., & Weinberg, D. S. (2015). Quality indicators for colonoscopy. Gastrointestinal Endoscopy, 81(1), 31-53. https://doi.org/10.1016/j.gie.2015.01.032
  5. 5.Royal Melbourne Hospital. (2024). Phase III Trial of AI-Assisted Colonoscopy for Colorectal Cancer Screening. ClinicalTrials.gov. https://clinicaltrials.gov/study/NCT-TEST-BLOG
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