Phase III Pilot Trial: Extended-Release Buprenorphine via Telemedicine for Incarcerated Patients — Bridging Jail-to-Community Treatment
247 Health News Editorial
·15 Apr 2026
·3 min read
·clinical-trialsA Phase III pilot study examines extended-release buprenorphine delivered via telemedicine for incarcerated patients transitioning to community care. The trial addresses critical treatment continuity gaps during the highest-risk period for overdose among justice-involved populations.
Originally reported by ClinicalTrials.gov
References
- 1.Australian Government Department of Health. (2023). Pharmaceutical Benefits Scheme: Buprenorphine. PBS Online. https://www.pbs.gov.au/medicine/item/8601E
- 2.Binswanger, I. A., Stern, M. F., Deyo, R. A., Heagerty, P. J., Cheadle, A., Elmore, J. G., & Koepsell, T. D. (2007). Release from prison—a high risk of death for former inmates. New England Journal of Medicine, 356(2), 157-165. https://doi.org/10.1056/NEJMsa064115
- 3.Friends Research Institute. (2024). An Open Label Pilot Study of Extended-release Buprenorphine (XR-B) Using Telemedicine With Individuals in Jail. ClinicalTrials.gov. NCT07524738. https://clinicaltrials.gov/study/NCT07524738
- 4.Lofwall, M. R., & Walsh, S. L. (2014). A review of buprenorphine diversion and misuse: the current evidence base and experiences from around the world. Journal of Addiction Medicine, 8(6), 403-424. https://doi.org/10.1097/ADM.0000000000000045
- 5.Marsden, J., Stillwell, G., Jones, H., Cooper, A., Eastwood, B., Farrell, M., ... & Strang, J. (2017). Does exposure to opioid substitution treatment in prison reduce the risk of death after release? A national prospective observational study in England. Addiction, 112(8), 1408-1418. https://doi.org/10.1111/add.13779
- 6.Ranapurwala, S. I., Shanahan, M. E., Alexandridis, A. A., Proescholdbell, S. K., Naumann, R. B., Edwards Jr, D., & Marshall, S. W. (2018). Opioid overdose mortality among former North Carolina inmates. American Journal of Public Health, 108(9), 1207-1209. https://doi.org/10.2105/AJPH.2017.304200
- 7.Substance Abuse and Mental Health Services Administration. (2021). Medications for Opioid Use Disorder Treatment Improvement Protocol (TIP) 63. SAMHSA Publication No. SMA21-4960. https://store.samhsa.gov/product/TIP-63-Medications-for-Opioid-Use-Disorder-TIP-63/SMA21-4960
- 8.Uscher-Pines, L., Sousa, J., Raja, P., Mehrotra, A., Barnett, M. L., & Huskamp, H. A. (2020). Suddenly becoming a 'virtual doctor': experiences of psychiatrists transitioning to telemedicine during the COVID-19 pandemic. Psychiatric Services, 71(11), 1143-1150. https://doi.org/10.1176/appi.ps.202000250
- 9.Wakeman, S. E., McKenzie, M., Jeronimo, A., & Rich, J. D. (2009). Implications of the prescription opioid epidemic for the criminal justice system. American Journal of Drug and Alcohol Abuse, 35(5), 327-331. https://doi.org/10.1080/00952990903005114
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247 Health News Editorial
247 Health News is a medical intelligence platform delivering evidence-based research appraisals, clinical trial monitoring, and health technology news for healthcare professionals.
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