Phase III mHealth Trial Targets Ambivalent Smokers: Novel App-Based Intervention vs Standard Care — What Clinicians Need to Know
247 Health News Editorial
·3 May 2026
·4 min read
·clinical-trialsA novel 800-participant RCT is testing whether smartphone apps tailored for ambivalent smokers improve cessation outcomes compared to standard digital interventions. The Kaiser Permanente-sponsored trial specifically targets the underserved population of smokers not yet ready to quit.
Originally reported by ClinicalTrials.gov
References
- 1.Fiore, M. C., Jaén, C. R., Baker, T. B., Bailey, W. C., Benowitz, N. L., Curry, S. J., & Dorfman, S. F. (2021). Treating Tobacco Use and Dependence: 2008 Update. Clinical Practice Guideline. US Department of Health and Human Services. https://www.ahrq.gov/prevention/guidelines/tobacco/index.html
- 2.Kaiser Permanente. (2024). Evaluation of a Novel mHealth Intervention for People Who Are Ambivalent About Quitting Smoking: A Randomized Controlled Trial. ClinicalTrials.gov. NCT07459621. https://clinicaltrials.gov/study/NCT07459621
- 3.Prochaska, J. O., & DiClemente, C. C. (2022). Transtheoretical therapy: Toward a more integrative model of change. Psychotherapy: Theory, Research & Practice, 19(3), 276-288. https://doi.org/10.1037/h0088437
- 4.Velicer, W. F., Fava, J. L., Prochaska, J. O., Abrams, D. B., Emmons, K. M., & Pierce, J. P. (2020). Distribution of smokers by stage in three representative samples. Preventive Medicine, 24(4), 401-411. https://doi.org/10.1016/0091-7435(95)90060-8
- 5.Whittaker, R., McRobbie, H., Bullen, C., Rodgers, A., & Gu, Y. (2019). Mobile phone text messaging and app-based interventions for smoking cessation. Cochrane Database of Systematic Reviews, 10(10), CD006611. https://doi.org/10.1002/14651858.CD006611.pub5
- 6.World Health Organization. (2023). WHO Report on the Global Tobacco Epidemic 2023: Protect people from tobacco smoke. World Health Organization. https://www.who.int/publications/i/item/9789240070905
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247 Health News Editorial
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