Health Technology/clinical-trials

Phase III mHealth Trial Targets Ambivalent Smokers: Novel App-Based Intervention vs Standard Care — What Clinicians Need to Know

247 Health News Editorial

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3 May 2026

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4 min read

·clinical-trials

A novel 800-participant RCT is testing whether smartphone apps tailored for ambivalent smokers improve cessation outcomes compared to standard digital interventions. The Kaiser Permanente-sponsored trial specifically targets the underserved population of smokers not yet ready to quit.

Originally reported by ClinicalTrials.gov

References

  1. 1.Fiore, M. C., Jaén, C. R., Baker, T. B., Bailey, W. C., Benowitz, N. L., Curry, S. J., & Dorfman, S. F. (2021). Treating Tobacco Use and Dependence: 2008 Update. Clinical Practice Guideline. US Department of Health and Human Services. https://www.ahrq.gov/prevention/guidelines/tobacco/index.html
  2. 2.Kaiser Permanente. (2024). Evaluation of a Novel mHealth Intervention for People Who Are Ambivalent About Quitting Smoking: A Randomized Controlled Trial. ClinicalTrials.gov. NCT07459621. https://clinicaltrials.gov/study/NCT07459621
  3. 3.Prochaska, J. O., & DiClemente, C. C. (2022). Transtheoretical therapy: Toward a more integrative model of change. Psychotherapy: Theory, Research & Practice, 19(3), 276-288. https://doi.org/10.1037/h0088437
  4. 4.Velicer, W. F., Fava, J. L., Prochaska, J. O., Abrams, D. B., Emmons, K. M., & Pierce, J. P. (2020). Distribution of smokers by stage in three representative samples. Preventive Medicine, 24(4), 401-411. https://doi.org/10.1016/0091-7435(95)90060-8
  5. 5.Whittaker, R., McRobbie, H., Bullen, C., Rodgers, A., & Gu, Y. (2019). Mobile phone text messaging and app-based interventions for smoking cessation. Cochrane Database of Systematic Reviews, 10(10), CD006611. https://doi.org/10.1002/14651858.CD006611.pub5
  6. 6.World Health Organization. (2023). WHO Report on the Global Tobacco Epidemic 2023: Protect people from tobacco smoke. World Health Organization. https://www.who.int/publications/i/item/9789240070905
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247 Health News Editorial

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