Health Technology/clinical-trials

Phase II Trial Opens: Brief Pain Exposure Therapy vs Standard Care in Nociplastic Pain Conditions — What Clinicians Need to Know

247 Health News Editorial

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19 May 2026

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4 min read

·clinical-trials

University of Michigan launches innovative telehealth trial testing Brief Pain Exposure Therapy for fibromyalgia, lupus, and chronic pain conditions. This novel approach could transform accessible pain management through streamlined digital delivery.

Originally reported by ClinicalTrials.gov

References

  1. 1.University of Michigan. (2024). Brief Pain Exposure Therapy (BPET) For Nociplastic Pain. ClinicalTrials.gov. https://clinicaltrials.gov/study/NCT06208514
  2. 2.Vlaeyen, J. W., & Linton, S. J. (2012). Fear-avoidance model of chronic musculoskeletal pain: 12 years on. Pain, 153(6), 1144-1147. https://doi.org/10.1016/j.pain.2012.05.024
  3. 3.Williams, A. C., Eccleston, C., & Morley, S. (2012). Psychological therapies for the management of chronic pain (excluding headache) in adults. Cochrane Database of Systematic Reviews, 11, CD007407. https://doi.org/10.1002/14651858.CD007407.pub3
  4. 4.Kosek, E., Cohen, M., Baron, R., Gebhart, G. F., Mico, J. A., Rice, A. S., Rief, W., & Sluka, A. K. (2016). Do we need a third mechanistic descriptor for chronic pain states? Pain, 157(7), 1382-1386. https://doi.org/10.1097/j.pain.0000000000000507
  5. 5.Ford, I., & Norrie, J. (2016). Pragmatic Trials. New England Journal of Medicine, 375(5), 454-463. https://doi.org/10.1056/NEJMra1510059
  6. 6.Turk, D. C., Dworkin, R. H., Allen, R. R., Bellamy, N., Brandenburg, N., Carr, D. B., Cleeland, C., Dionne, R., Farrar, J. T., Galer, B. S., Hewitt, D. J., Jadad, A. R., Katz, N. P., Kramer, L. D., Manning, D. C., McCormick, C. G., McDermott, M. P., McGrath, P., Quessy, S., ... Witter, J. (2003). Core outcome domains for chronic pain clinical trials: IMMPACT recommendations. Pain, 106(3), 337-345. https://doi.org/10.1016/j.pain.2003.08.001
  7. 7.Häuser, W., Ablin, J., Fitzcharles, M. A., Littlejohn, G., Luciano, J. V., Usui, C., & Walitt, B. (2015). Fibromyalgia. Nature Reviews Disease Primers, 1, 15022. https://doi.org/10.1038/nrdp.2015.22
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247 Health News Editorial

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