Health Technology/clinical-trials

Phase II RCT Opens: Digital CBT-I vs Sleep Hygiene for Post-Concussion Insomnia — Novel Brain-Heart Monitoring Approach

247 Health News Editorial

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26 June 2026

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4 min read

·clinical-trials

New RCT investigates digital CBT-I versus sleep hygiene for post-concussion insomnia, using innovative brain-heart monitoring. 70-patient Canadian study targets persistent sleep disturbances following mild traumatic brain injury.

Originally reported by ClinicalTrials.gov

References

  1. 1.University of Ottawa. (2024). Enhancing sleep to improve brain-heart functions in people with persistent post-concussion symptoms. ClinicalTrials.gov. NCT07636408. https://clinicaltrials.gov/study/NCT07636408
  2. 2.Theadom, A., Parag, V., Dowell, T., McPherson, K., Starkey, N., Barker-Collo, S., ... & Feigin, V. L. (2016). Persistent problems 1 year after mild traumatic brain injury: a longitudinal population study in New Zealand. British Journal of General Practice, 66(642), e16-e23. https://doi.org/10.3399/bjgp16X684301
  3. 3.Wickwire, E. M., Williams, S. G., Roth, T., Capaldi, V. F., Jaffe, M., Moline, M., ... & Lettieri, C. J. (2016). Sleep, sleep disorders, and mild traumatic brain injury: what we know and what we need to know. Neurotherapeutics, 13(2), 403-417. https://doi.org/10.1007/s13311-016-0429-3
  4. 4.Mollayeva, T., Kendzerska, T., Mollayeva, S., Shapiro, C. M., Colantonio, A., & Cassidy, J. D. (2014). A systematic review of fatigue in patients with traumatic brain injury: the course, predictors and consequences. Neuropsychological Rehabilitation, 24(3-4), 409-427. https://doi.org/10.1080/09602011.2014.890326
  5. 5.Trauer, J. M., Qian, M. Y., Doyle, J. S., Rajaratnam, S. M., & Cunnington, D. (2015). Cognitive behavioral therapy for chronic insomnia: a systematic review and meta-analysis. Annals of Internal Medicine, 163(3), 191-204. https://doi.org/10.7326/M14-2841
  6. 6.La Fountaine, M. F., Heffernan, T. P., Gossett, J. D., Tulppo, M. P., & Convertino, V. A. (2016). Transient suppression of heart rate complexity in concussed athletes. Autonomic Neuroscience, 197, 1-6. https://doi.org/10.1016/j.autneu.2015.03.001
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