Health Technology/clinical-trials

Phase I Trial Opens: Percepta Supplement vs Placebo in Mild Cognitive Impairment — Digital MoCA Primary Endpoint

247 Health News Editorial

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16 June 2026

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3 min read

·clinical-trials

New Phase I trial investigates Percepta supplement containing cat's claw and oolong tea extracts versus placebo in 154 adults with mild cognitive impairment. The decentralised study uses digital MoCA assessments and Oura Ring monitoring over six months.

Originally reported by ClinicalTrials.gov

References

  1. 1.Cerebrum DAO Association. (2024). Percepta for Cognitive Optimization: A 6-Month Randomized Controlled Trial With Neurocognitive, Wearable, and Participant-Reported Outcomes in Adults With Mild Cognitive Impairment. ClinicalTrials.gov. NCT07612449. https://clinicaltrials.gov/study/NCT07612449
  2. 2.Langa, K. M., & Levine, D. A. (2014). The diagnosis and management of mild cognitive impairment: a clinical review. JAMA, 312(23), 2551-2561. https://doi.org/10.1001/jama.2014.13806
  3. 3.Petersen, R. C., Lopez, O., Armstrong, M. J., Getchius, T. S., Ganguli, M., Gloss, D., ... & Rae-Grant, A. (2018). Practice guideline update summary: Mild cognitive impairment. Neurology, 90(3), 126-135. https://doi.org/10.1212/WNL.0000000000004826
  4. 4.Tricco, A. C., Soobiah, C., Berliner, S., Ho, J. M., Ng, C. H., Ashoor, H. M., ... & Straus, S. E. (2013). Efficacy and safety of cognitive enhancers for patients with mild cognitive impairment: a systematic review and meta-analysis. CMAJ, 185(16), 1393-1401. https://doi.org/10.1503/cmaj.130451
  5. 5.Zhang, Y., Li, P., Wang, L., & Chen, H. (2023). Neuroprotective effects of Uncaria tomentosa alkaloids in neurodegenerative diseases: A systematic review. Phytomedicine, 115, 154821. https://doi.org/10.1016/j.phymed.2023.154821
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