Health Technology/clinical-trials

Phase I Trial Opens: Acceptance and Commitment Therapy for Dementia Patients and Caregivers — What Clinicians Need to Know

247 Health News Editorial

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23 May 2026

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3 min read

·clinical-trials

New Phase I trial evaluates Acceptance and Commitment Therapy for dementia patients and their caregivers together. The dyadic approach addresses depression, anxiety, and grief in both parties simultaneously through in-person and telehealth delivery.

Originally reported by ClinicalTrials.gov

References

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  2. 2.Folstein, M. F., Folstein, S. E., & McHugh, P. R. (1975). Mini-mental state: A practical method for grading the cognitive state of patients for the clinician. Journal of Psychiatric Research, 12(3), 189-198. https://doi.org/10.1016/0022-3956(75)90026-6
  3. 3.Hayes, S. C., Luoma, J. B., Bond, F. W., Masuda, A., & Lillis, J. (2006). Acceptance and commitment therapy: Model, processes and outcomes. Behaviour Research and Therapy, 44(1), 1-25. https://doi.org/10.1016/j.brat.2005.06.006
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  6. 6.Royal Australian College of General Practitioners. (2023). Telehealth guidelines for general practice. RACGP. https://www.racgp.org.au/clinical-resources/clinical-guidelines/key-racgp-guidelines/view-all-racgp-guidelines/telehealth
  7. 7.Schneider, L. S., Dagerman, K., & Insel, P. S. (2006). Efficacy and adverse effects of atypical antipsychotics for dementia: Meta-analysis of randomized, placebo-controlled trials. American Journal of Geriatric Psychiatry, 14(3), 191-210. https://doi.org/10.1097/01.JGP.0000200589.01396.6d
  8. 8.Spector, A., Charlesworth, G., King, M., Lattimer, M., Sadek, S., Marston, L., ... & Orrell, M. (2015). Cognitive-behavioural therapy for anxiety in dementia: Pilot randomised controlled trial. British Journal of Psychiatry, 206(6), 509-516. https://doi.org/10.1192/bjp.bp.113.140087
  9. 9.Texas Tech University. (2024). Acceptance and Commitment Therapy for Individuals With MNCD and Their Care Partners. ClinicalTrials.gov. NCT07239609. https://clinicaltrials.gov/study/NCT07239609
  10. 10.Zhao, Q. F., Tan, L., Wang, H. F., Jiang, T., Tan, M. S., Tan, L., ... & Yu, J. T. (2016). The prevalence of neuropsychiatric symptoms in Alzheimer's disease: Systematic review and meta-analysis. Journal of Affective Disorders, 190, 264-271. https://doi.org/10.1016/j.jad.2015.09.069
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247 Health News Editorial

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