Health Technology/clinical-trials

Oxford AI-Enhanced Blood Biomarker Study for Lung Cancer Diagnosis — Implications for Australian Screening Programs

247 Health News Editorial

·

1 June 2026

·

3 min read

·clinical-trials

Oxford researchers are developing AI-enhanced blood biomarker tests to improve lung cancer diagnosis in screening programs. This 872-patient study could revolutionise how clinicians evaluate suspicious pulmonary nodules.

Originally reported by ClinicalTrials.gov

References

  1. 1.University of Oxford. (2024). Sample Collection for The Integration and Analysis of Data Using Artificial Intelligence to Improve Patient Outcomes With Thoracic Diseases. ClinicalTrials.gov. NCT05368298. https://clinicaltrials.gov/study/NCT05368298
  2. 2.Mazzone, P. J., Silvestri, G. A., Patel, S., Kanne, J. P., Kinsinger, L. S., Wiener, R. S., Soo Hoo, G., Detterbeck, F. C., Jackman, D. M., Munden, R. F., Tanner, N. T., Ahmad, U., Blackstock, A. W., Butler, M., Gesthalter, Y., Gould, M., Iaccarino, J. M., Janes, S. M., Kazerooni, E. A., ... American College of Chest Physicians. (2018). Screening for Lung Cancer: CHEST Guideline and Expert Panel Report. Chest, 153(4), 954-985. https://doi.org/10.1016/j.chest.2018.01.016
  3. 3.Cohen, J. D., Li, L., Wang, Y., Thoburn, C., Afsari, B., Danilova, L., Douville, C., Javed, A. A., Wong, F., Mattox, A., Hruban, R. H., Wolfgang, C. L., Goggins, M. G., Dal Molin, M., Wang, T. L., Roden, R., Klein, A. P., Ptak, J., Dobbyn, L., ... Papadopoulos, N. (2018). Detection and localization of surgically resectable cancers with a multi-analyte blood test. Science, 359(6378), 926-930. https://doi.org/10.1126/science.aar3247
  4. 4.Ardila, D., Kiraly, A. P., Bharadwaj, S., Choi, B., Reicher, J. J., Peng, L., Tse, D., Etemadi, M., Ye, W., Corrado, G., Naidich, D. P., & Shetty, S. (2019). End-to-end lung cancer screening with three-dimensional deep learning on low-dose chest computed tomography. Nature Medicine, 25(6), 954-961. https://doi.org/10.1038/s41591-019-0447-x
  5. 5.MacMahon, H., Naidich, D. P., Goo, J. M., Lee, K. S., Leung, A. N., Mayo, J. R., Mehta, A. C., Ohno, Y., Powell, C. A., Prokop, M., Rubin, G. D., Schaefer-Prokop, C. M., Travis, W. D., Van Schil, P. E., & Bankier, A. A. (2017). Guidelines for Management of Incidental Pulmonary Nodules Detected on CT Images. Radiology, 284(1), 228-243. https://doi.org/10.1148/radiol.2017161659
  6. 6.Sung, H., Ferlay, J., Siegel, R. L., Laversanne, M., Soerjomataram, I., Jemal, A., & Bray, F. (2021). Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA: A Cancer Journal for Clinicians, 71(3), 209-249. https://doi.org/10.3322/caac.21660
Share:XLinkedIn
2

247 Health News Editorial

247 Health News is a medical intelligence platform delivering evidence-based research appraisals, clinical trial monitoring, and health technology news for healthcare professionals.

This content is for educational purposes for healthcare professionals only and does not constitute clinical advice. Clinical decisions should be based on individual patient assessment, current guidelines, and appropriate specialist consultation. Editorial Standards · Privacy Policy · Terms of Service