Oxford AI-Enhanced Blood Biomarker Study for Lung Cancer Diagnosis — Implications for Australian Screening Programs
247 Health News Editorial
·1 June 2026
·3 min read
·clinical-trialsOxford researchers are developing AI-enhanced blood biomarker tests to improve lung cancer diagnosis in screening programs. This 872-patient study could revolutionise how clinicians evaluate suspicious pulmonary nodules.
Originally reported by ClinicalTrials.gov
References
- 1.University of Oxford. (2024). Sample Collection for The Integration and Analysis of Data Using Artificial Intelligence to Improve Patient Outcomes With Thoracic Diseases. ClinicalTrials.gov. NCT05368298. https://clinicaltrials.gov/study/NCT05368298
- 2.Mazzone, P. J., Silvestri, G. A., Patel, S., Kanne, J. P., Kinsinger, L. S., Wiener, R. S., Soo Hoo, G., Detterbeck, F. C., Jackman, D. M., Munden, R. F., Tanner, N. T., Ahmad, U., Blackstock, A. W., Butler, M., Gesthalter, Y., Gould, M., Iaccarino, J. M., Janes, S. M., Kazerooni, E. A., ... American College of Chest Physicians. (2018). Screening for Lung Cancer: CHEST Guideline and Expert Panel Report. Chest, 153(4), 954-985. https://doi.org/10.1016/j.chest.2018.01.016
- 3.Cohen, J. D., Li, L., Wang, Y., Thoburn, C., Afsari, B., Danilova, L., Douville, C., Javed, A. A., Wong, F., Mattox, A., Hruban, R. H., Wolfgang, C. L., Goggins, M. G., Dal Molin, M., Wang, T. L., Roden, R., Klein, A. P., Ptak, J., Dobbyn, L., ... Papadopoulos, N. (2018). Detection and localization of surgically resectable cancers with a multi-analyte blood test. Science, 359(6378), 926-930. https://doi.org/10.1126/science.aar3247
- 4.Ardila, D., Kiraly, A. P., Bharadwaj, S., Choi, B., Reicher, J. J., Peng, L., Tse, D., Etemadi, M., Ye, W., Corrado, G., Naidich, D. P., & Shetty, S. (2019). End-to-end lung cancer screening with three-dimensional deep learning on low-dose chest computed tomography. Nature Medicine, 25(6), 954-961. https://doi.org/10.1038/s41591-019-0447-x
- 5.MacMahon, H., Naidich, D. P., Goo, J. M., Lee, K. S., Leung, A. N., Mayo, J. R., Mehta, A. C., Ohno, Y., Powell, C. A., Prokop, M., Rubin, G. D., Schaefer-Prokop, C. M., Travis, W. D., Van Schil, P. E., & Bankier, A. A. (2017). Guidelines for Management of Incidental Pulmonary Nodules Detected on CT Images. Radiology, 284(1), 228-243. https://doi.org/10.1148/radiol.2017161659
- 6.Sung, H., Ferlay, J., Siegel, R. L., Laversanne, M., Soerjomataram, I., Jemal, A., & Bray, F. (2021). Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA: A Cancer Journal for Clinicians, 71(3), 209-249. https://doi.org/10.3322/caac.21660
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247 Health News Editorial
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