Health Technology/clinical-trials

Observational Study Launches: Machine Learning to Classify Intraoperative Hypotension Endotypes — Implications for Personalised Anaesthetic Management

247 Health News Editorial

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11 Apr 2026

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4 min read

·clinical-trials

Turkish researchers launch observational study using machine learning to classify intraoperative hypotension subtypes, potentially enabling personalised anaesthetic management. The study aims to identify distinct physiological mechanisms underlying hypotensive episodes during surgery.

Originally reported by ClinicalTrials.gov

References

  1. 1.Maheshwari, K., Turan, A., Mao, G., Yang, D., Niazi, A. K., Agarwal, D., Bose, S., Ruetzler, K., Qiu, Y., Silverton, N., Rivas, E., Saager, L., You, J., Kurz, A., & Sessler, D. I. (2020). The association of hypotension during non-cardiac surgery, before and after skin incision, with postoperative acute kidney injury. Anaesthesia, 75(2), 187-195. https://doi.org/10.1111/anae.14934
  2. 2.Nevsehir Public Hospital. (2024). Machine Learning-Assisted Intraoperative Hypotension Management: Developing Personalized Treatment Recommendations. ClinicalTrials.gov. NCT07396636. https://clinicaltrials.gov/study/NCT07396636
  3. 3.Salmasi, V., Maheshwari, K., Yang, D., Mascha, E. J., Singh, A., Sessler, D. I., & Kurz, A. (2017). Relationship between intraoperative hypotension, defined by either reduction from baseline or absolute thresholds, and acute kidney and myocardial injury after noncardiac surgery. Anesthesiology, 127(1), 47-55. https://doi.org/10.1097/ALN.0000000000001432
  4. 4.Sessler, D. I., Bloomstone, J. A., Aronson, S., Berry, C., Gan, T. J., Kellum, J. A., Plumb, J., Mythen, M. G., Grocott, M. P., Edwards, M. R., Miller, T. E., & Perioperative Quality Initiative-3 Workgroup. (2019). Perioperative Quality Initiative consensus statement on intraoperative blood pressure, risk and outcomes for elective surgery. British Journal of Anaesthesia, 122(5), 563-574. https://doi.org/10.1016/j.bja.2019.01.013
  5. 5.Wesselink, E. M., Kappen, T. H., Torn, H. M., Slooter, A. J., & van Klei, W. A. (2018). Intraoperative hypotension and the risk of postoperative adverse outcomes: a systematic review. British Journal of Anaesthesia, 121(4), 706-721. https://doi.org/10.1016/j.bja.2018.04.036
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