Novel Hospital-at-Home Trial Opens for Small Cell Lung Cancer Patients Receiving Tarlatamab — What Oncologists Need to Know
247 Health News Editorial
·25 June 2026
·4 min read
·clinical-trialsThe MATCHES-Novel trial is investigating whether Hospital-at-Home delivery of tarlatamab for small cell lung cancer can reduce hospitalisation while maintaining safety. This innovative study could transform how complex immunotherapies are administered.
Originally reported by ClinicalTrials.gov
References
- 1.Memorial Sloan Kettering Cancer Center. (2024). MATCHES-Novel: MAking Telehealth Delivery of Cancer Care at Home Effective and Safe for Novel Therapies: A Hospital-at-Home Model for Tarlatamab Delivery. ClinicalTrials.gov. NCT06957314. https://clinicaltrials.gov/study/NCT06957314
- 2.Ahn, M. J., Cho, B. C., Felip, E., Korantzis, I., Ohashi, K., Majem, M., Juan-Vidal, O., Handzhiev, S., Izumi, H., Lee, J. S., Tanaka, H., Laktionov, K., Shire, N., Trukhin, D., Cicin, I., Dakhil, S., Ponce, S., Muñoz, J., Peguero, J., ... Paz-Ares, L. (2023). Tarlatamab for patients with previously treated small-cell lung cancer. New England Journal of Medicine, 389(22), 2063-2075. https://doi.org/10.1056/NEJMoa2307980
- 3.Levine, D. M., Ouchi, K., Blanchfield, B., Diamond, K., Bachovchin, K., Pu, C. T., & Schnipper, J. L. (2020). Hospital-level care at home for acutely ill adults: a randomised controlled trial. The Lancet, 395(10233), 1397-1406. https://doi.org/10.1016/S0140-6736(20)31662-8
- 4.Rudin, C. M., Brambilla, E., Faivre-Finn, C., & Sage, J. (2021). Small-cell lung cancer. Nature Reviews Disease Primers, 7(1), 3. https://doi.org/10.1038/s41572-020-00235-0
- 5.Caplan, G. A., Sulaiman, N. S., Mangin, D. A., Aimonino Ricauda, N., Wilson, A. D., & Barclay, L. (2012). A meta-analysis of 'hospital in the home'. Medical Journal of Australia, 197(9), 512-519. https://doi.org/10.5694/mja11.10480
2
247 Health News Editorial
247 Health News is a medical intelligence platform delivering evidence-based research appraisals, clinical trial monitoring, and health technology news for healthcare professionals.
Related Articles
clinical-trials
Digital Health Platform vs Case Manager Support in Hypertension Management: Taiwan's 1,726-Participant Trial Signals a Shift in Blood Pressure Care Delivery
3 Aug 2026
clinical-trials
Phase II Trial: AI-Powered Wysa Chatbot vs Unmet Need — Digital Eating Disorder Prevention in At-Risk Adolescents
3 Aug 2026
clinical-trials
Pilot Trial Targets the Inpatient-to-Outpatient Gap: Digital Smoking Cessation Intervention for Persons With Serious Mental Illness — Key Findings for Clinicians
3 Aug 2026
This content is for educational purposes for healthcare professionals only and does not constitute clinical advice. Clinical decisions should be based on individual patient assessment, current guidelines, and appropriate specialist consultation. Editorial Standards · Privacy Policy · Terms of Service