Novel ECG Analysis Trial Aims to Revolutionise Coronary Stenosis Screening — Russian Study Tests AI-Enhanced Single-Lead Detection
247 Health News Editorial
·18 May 2026
·3 min read
·clinical-trialsRussian researchers are testing whether advanced analysis of single-lead ECG recordings can accurately detect significant coronary artery stenosis. The 400-patient study compares spectral ECG analysis against gold-standard coronary imaging.
Originally reported by ClinicalTrials.gov
References
- 1.I.M. Sechenov First Moscow State Medical University. (2024). Screening for Significant Coronary Artery Stenosis Using Single-channel Electrocardiogram Analysis With Artificial Intelligence Elements. ClinicalTrials.gov. NCT07579624. https://clinicaltrials.gov/study/NCT07579624
- 2.Fihn, S. D., Gardin, J. M., Abrams, J., Berra, K., Blankenship, J. C., Dallas, A. P., Douglas, P. S., Foody, J. M., Gerber, T. C., Hinderliter, A. L., King, S. B., Kligfield, P. D., Krumholz, H. M., Kwong, R. Y., Lim, M. J., Linderbaum, J. A., Mack, M. J., Munger, M. A., Prager, R. L., ... Williams, S. V. (2012). 2012 ACCF/AHA/ACP/AATS/PCNA/SCAI/STS guideline for the diagnosis and management of patients with stable ischemic heart disease. Circulation, 126(25), e354-e471. https://doi.org/10.1161/CIR.0b013e318277d6a0
- 3.Gianrossi, R., Detrano, R., Mulvihill, D., Lehmann, K., Dubach, P., Colombo, A., McArthur, D., & Froelicher, V. (1989). Exercise-induced ST depression in the diagnosis of coronary artery disease: a meta-analysis. Circulation, 80(1), 87-98. https://doi.org/10.1161/01.CIR.80.1.87
- 4.Knuuti, J., Wijns, W., Saraste, A., Capodanno, D., Barbato, E., Funck-Brentano, C., Prescott, E., Storey, R. F., Deaton, C., Cuisset, T., Agewall, S., Dickstein, K., Edvardsen, T., Escaned, J., Gersh, B. J., Svitil, P., Gilard, M., Hasdai, D., Hatala, R., ... Windecker, S. (2020). 2019 ESC Guidelines for the diagnosis and management of chronic coronary syndromes. European Heart Journal, 41(3), 407-477. https://doi.org/10.1093/eurheartj/ehz425
- 5.Montalescot, G., Sechtem, U., Achenbach, S., Andreotti, F., Arden, C., Budaj, A., Bugiardini, R., Crea, F., Cuisset, T., Di Mario, C., Ferreira, J. R., Gersh, B. J., Gitt, A. K., Hulot, J. S., Marx, N., Opie, L. H., Pfisterer, M., Prescott, E., Ruschitzka, F., ... Windecker, S. (2013). 2013 ESC guidelines on the management of stable coronary artery disease. European Heart Journal, 34(38), 2949-3003. https://doi.org/10.1093/eurheartj/eht296
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