Health Technology/clinical-trials

Novel Digital Exercise Prescription Tool P3-EX Enters Feasibility Trial for Cardiovascular Risk Management — What Clinicians Need to Know

247 Health News Editorial

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17 Apr 2026

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4 min read

·clinical-trials

University of Connecticut researchers are testing P3-EX, a novel digital tool designed to help physicians prescribe personalized exercise programs to patients with cardiovascular risk factors. The crossover trial compares this innovative approach against standard ACSM guidelines.

Originally reported by ClinicalTrials.gov

References

  1. 1.Lee, I. M., Shiroma, E. J., Lobelo, F., Puska, P., Blair, S. N., & Katzmarzyk, P. T. (2012). Effect of physical inactivity on major non-communicable diseases worldwide: an analysis of burden of disease and life expectancy. The Lancet, 380(9838), 219-229. https://doi.org/10.1016/S0140-6736(12)61031-9
  2. 2.Lobelo, F., Stoutenberg, M., & Hutber, A. (2014). The evidence in support of physicians and health care providers as physical activity counselors. American Journal of Lifestyle Medicine, 8(5), 295-298. https://doi.org/10.1177/1559827613520120
  3. 3.Naci, H., & Ioannidis, J. P. (2013). Comparative effectiveness of exercise and drug interventions on mortality outcomes: metaepidemiological study. BMJ, 347, f5577. https://doi.org/10.1136/bmj.f5577
  4. 4.Piercy, K. L., Troiano, R. P., Ballard, R. M., Carlson, S. A., Fulton, J. E., Galuska, D. A., ... & Olson, R. D. (2018). The Physical Activity Guidelines for Americans. JAMA, 320(19), 2020-2028. https://doi.org/10.1001/jama.2018.14854
  5. 5.University of Connecticut. (2024). Feasibility and Acceptability of a Novel Algorithm for Physicians to Prescribe Personalized Exercise Prescriptions to Patients With Cardiovascular Disease Risk Factors. ClinicalTrials.gov. NCT07238556. https://clinicaltrials.gov/study/NCT07238556
  6. 6.Warburton, D. E., & Bredin, S. S. (2017). Health benefits of physical activity: a systematic review of current systematic reviews. Current Opinion in Cardiology, 32(5), 541-556. https://doi.org/10.1097/HCO.0000000000000437
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247 Health News Editorial

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