Novel Biomarker Study: Heart Rate Variability to Predict Sleep Apnea Severity in Hypertensive Patients — Implications for Australian Practice
247 Health News Editorial
·1 June 2026
·4 min read
·clinical-trialsTaiwanese researchers investigate heart rate variability as a potential biomarker for predicting sleep apnea severity in hypertensive patients. This novel approach could revolutionise OSA screening using readily available cardiac monitoring equipment.
Originally reported by ClinicalTrials.gov
References
- 1.Kaohsiung Armed Forces General Hospital. (2024). The exploration of the relationship between hypertension and sleep apnea through heart rate variability, and the subsequent investigation of non-pharmacological and pharmacological treatments. ClinicalTrials.gov. https://clinicaltrials.gov/study/NCT07603583
- 2.Calhoun, D. A., & Harding, S. M. (2010). Sleep and hypertension. Chest, 138(2), 434-443. https://doi.org/10.1378/chest.09-2954
- 3.Gula, L. J., Krahn, A. D., Skanes, A., Ferguson, K. A., George, C., Yee, R., & Klein, G. J. (2003). Heart rate variability in obstructive sleep apnea: a prospective study and frequency domain analysis. Annals of Noninvasive Electrocardiology, 8(4), 274-279. https://doi.org/10.1046/j.1542-474X.2003.08411.x
- 4.Chung, F., Abdullah, H. R., & Liao, P. (2016). STOP-Bang questionnaire: a practical approach to screen for obstructive sleep apnea. Chest, 149(3), 631-638. https://doi.org/10.1016/j.chest.2016.05.019
- 5.Logan, A. G., Perlikowski, S. M., Mente, A., Tisler, A., Tkacova, R., Niroumand, M., ... & Bradley, T. D. (2001). High prevalence of unrecognized sleep apnoea in drug-resistant hypertension. Journal of Hypertension, 19(12), 2271-2277. https://doi.org/10.1097/00004872-200112000-00022
- 6.Chai-Coetzer, C. L., Antic, N. A., Rowland, L. S., Reed, R. L., Esterman, A., Catcheside, P. G., ... & McEvoy, R. D. (2013). A simplified model of screening questionnaire and home monitoring for obstructive sleep apnoea in primary care. Thorax, 68(9), 855-862. https://doi.org/10.1136/thoraxjnl-2013-203463
- 7.Deloitte Access Economics. (2019). Sleep health foundation: Asleep on the job: costs of inadequate sleep in Australia. Sleep Health Foundation. https://www.sleephealthfoundation.org.au/files/pdfs/Asleep-on-the-Job-Report-2017.pdf
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247 Health News Editorial
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