Health Technology/clinical-trials

Novel Biomarker Study: Heart Rate Variability to Predict Sleep Apnea Severity in Hypertensive Patients — Implications for Australian Practice

247 Health News Editorial

·

1 June 2026

·

4 min read

·clinical-trials

Taiwanese researchers investigate heart rate variability as a potential biomarker for predicting sleep apnea severity in hypertensive patients. This novel approach could revolutionise OSA screening using readily available cardiac monitoring equipment.

Originally reported by ClinicalTrials.gov

References

  1. 1.Kaohsiung Armed Forces General Hospital. (2024). The exploration of the relationship between hypertension and sleep apnea through heart rate variability, and the subsequent investigation of non-pharmacological and pharmacological treatments. ClinicalTrials.gov. https://clinicaltrials.gov/study/NCT07603583
  2. 2.Calhoun, D. A., & Harding, S. M. (2010). Sleep and hypertension. Chest, 138(2), 434-443. https://doi.org/10.1378/chest.09-2954
  3. 3.Gula, L. J., Krahn, A. D., Skanes, A., Ferguson, K. A., George, C., Yee, R., & Klein, G. J. (2003). Heart rate variability in obstructive sleep apnea: a prospective study and frequency domain analysis. Annals of Noninvasive Electrocardiology, 8(4), 274-279. https://doi.org/10.1046/j.1542-474X.2003.08411.x
  4. 4.Chung, F., Abdullah, H. R., & Liao, P. (2016). STOP-Bang questionnaire: a practical approach to screen for obstructive sleep apnea. Chest, 149(3), 631-638. https://doi.org/10.1016/j.chest.2016.05.019
  5. 5.Logan, A. G., Perlikowski, S. M., Mente, A., Tisler, A., Tkacova, R., Niroumand, M., ... & Bradley, T. D. (2001). High prevalence of unrecognized sleep apnoea in drug-resistant hypertension. Journal of Hypertension, 19(12), 2271-2277. https://doi.org/10.1097/00004872-200112000-00022
  6. 6.Chai-Coetzer, C. L., Antic, N. A., Rowland, L. S., Reed, R. L., Esterman, A., Catcheside, P. G., ... & McEvoy, R. D. (2013). A simplified model of screening questionnaire and home monitoring for obstructive sleep apnoea in primary care. Thorax, 68(9), 855-862. https://doi.org/10.1136/thoraxjnl-2013-203463
  7. 7.Deloitte Access Economics. (2019). Sleep health foundation: Asleep on the job: costs of inadequate sleep in Australia. Sleep Health Foundation. https://www.sleephealthfoundation.org.au/files/pdfs/Asleep-on-the-Job-Report-2017.pdf
Share:XLinkedIn
2

247 Health News Editorial

247 Health News is a medical intelligence platform delivering evidence-based research appraisals, clinical trial monitoring, and health technology news for healthcare professionals.

This content is for educational purposes for healthcare professionals only and does not constitute clinical advice. Clinical decisions should be based on individual patient assessment, current guidelines, and appropriate specialist consultation. Editorial Standards · Privacy Policy · Terms of Service