Novel Accelerometer Algorithm Validation Trial Opens: Improving Energy Expenditure Assessment in Movement Disorders — What Clinicians Need to Know
247 Health News Editorial
·10 May 2026
·3 min read
·clinical-trialsNew validation study tests machine-learned accelerometer algorithms against gold standard doubly-labeled water method in movement disorder patients. Could revolutionise energy expenditure assessment in clinical practice.
Originally reported by ClinicalTrials.gov
References
- 1.Bassett Jr, D. R., Rowlands, A., & Trost, S. G. (2012). Calibration and validation of wearable monitors. Medicine & Science in Sports & Exercise, 44(1), S32-S38. https://doi.org/10.1249/MSS.0b013e318258cb36
- 2.Crouter, S. E., Clowers, K. G., & Bassett, D. R. (2006). A novel method for using accelerometer data to predict energy expenditure. Journal of Applied Physiology, 100(4), 1324-1331. https://doi.org/10.1152/japplphysiol.00818.2005
- 3.Speakman, J. R. (1997). Doubly labelled water: theory and practice. Chapman & Hall. https://doi.org/10.1007/978-94-009-1402-1
- 4.Speelman, A. D., van de Warrenburg, B. P., van Nimwegen, M., Petzinger, G. M., Munneke, M., & Bloem, B. R. (2011). How might physical activity benefit patients with Parkinson disease? Nature Reviews Neurology, 7(9), 478-484. https://doi.org/10.1038/nrneurol.2011.107
- 5.Storm, F. A., Heller, B. W., & Mazzà, C. (2015). Step detection and activity recognition accuracy of seven physical activity monitors. PLoS One, 10(3), e0118723. https://doi.org/10.1371/journal.pone.0118723
- 6.University of Wisconsin, Milwaukee. (2024). Validating a New Machine-Learned Accelerometer Algorithm Using Doubly Labeled Water. ClinicalTrials.gov. NCT05736302. https://clinicaltrials.gov/study/NCT05736302
- 7.Van Remoortel, H., Giavedoni, S., Raste, Y., Burtin, C., Louvaris, Z., Gimeno-Santos, E., ... & Troosters, T. (2012). Validity of activity monitors in health and chronic disease: a systematic review. International Journal of Behavioral Nutrition and Physical Activity, 9(1), 84. https://doi.org/10.1186/1479-5868-9-84
- 8.Westerterp, K. R. (2017). Doubly labelled water assessment of energy expenditure: principle, practice, and promise. European Journal of Applied Physiology, 117(7), 1277-1285. https://doi.org/10.1007/s00421-017-3641-x
2
247 Health News Editorial
247 Health News is a medical intelligence platform delivering evidence-based research appraisals, clinical trial monitoring, and health technology news for healthcare professionals.
Related Articles
clinical-trials
Digital Health Platform vs Case Manager Support in Hypertension Management: Taiwan's 1,726-Participant Trial Signals a Shift in Blood Pressure Care Delivery
3 Aug 2026
clinical-trials
Phase II Trial: AI-Powered Wysa Chatbot vs Unmet Need — Digital Eating Disorder Prevention in At-Risk Adolescents
3 Aug 2026
clinical-trials
Pilot Trial Targets the Inpatient-to-Outpatient Gap: Digital Smoking Cessation Intervention for Persons With Serious Mental Illness — Key Findings for Clinicians
3 Aug 2026
This content is for educational purposes for healthcare professionals only and does not constitute clinical advice. Clinical decisions should be based on individual patient assessment, current guidelines, and appropriate specialist consultation. Editorial Standards · Privacy Policy · Terms of Service