Non-Inferiority Trial Tests Smart Toothbrush Regimen vs Professional Cleaning for Gingivitis Management
247 Health News Editorial
·27 Apr 2026
·4 min read
·clinical-trialsA Chinese non-inferiority trial is testing whether smart toothbrush technology can replace professional dental cleaning for gingivitis management. The study compares an app-connected electric toothbrush regimen alone versus combined with professional mechanical plaque removal in 92 participants.
Originally reported by ClinicalTrials.gov
References
- 1.Ainamo, J., & Bay, I. (1975). Problems and proposals for recording gingivitis and plaque. International Dental Journal, 25(4), 229-235.
- 2.Chapple, I. L., Mealey, B. L., Van Dyke, T. E., Bartold, P. M., Dommisch, H., Eickholz, P., ... & Yoshie, H. (2018). Periodontal health and gingival diseases and conditions on an intact and a reduced periodontium: Consensus report of workgroup 1 of the 2017 World Workshop on the Classification of Periodontal and Peri‐Implant Diseases and Conditions. Journal of Periodontology, 89(S1), S74-S84. https://doi.org/10.1002/JPER.17-0719
- 3.Kassebaum, N. J., Bernabé, E., Dahiya, M., Bhandari, B., Murray, C. J., & Marcenes, W. (2014). Global burden of severe periodontitis in 1990-2010: a systematic review and meta-regression. Journal of Dental Research, 93(11), 1045-1053. https://doi.org/10.1177/0022034514552491
- 4.Löe, H., Theilade, E., & Jensen, S. B. (1965). Experimental gingivitis in man. Journal of Periodontology, 36(3), 177-187. https://doi.org/10.1902/jop.1965.36.3.177
- 5.Shanghai Ninth People's Hospital. (2024). Optimal Oral Care Regimen With or Without Professional Mechanical Plaque Removal in Managing Gingivitis (Gingival Inflammation): A Non-inferiority Randomized Controlled Trial. ClinicalTrials.gov. https://clinicaltrials.gov/study/NCT07549347
- 6.Tonetti, M. S., Jepsen, S., Jin, L., & Otomo‐Corgel, J. (2017). Impact of the global burden of periodontal diseases on health, nutrition and wellbeing of mankind: A call for global action. Journal of Clinical Periodontology, 44(5), 456-462. https://doi.org/10.1111/jcpe.12732
- 7.Trombelli, L., Farina, R., Silva, C. O., & Tatakis, D. N. (2018). Plaque‐induced gingivitis: Case definition and diagnostic considerations. Journal of Periodontology, 89(S1), S46-S73. https://doi.org/10.1002/JPER.17-0576
- 8.Worthington, H. V., MacDonald, L., Poklepovic Pericic, T., Sambunjak, D., Johnson, T. M., Imai, P., & Clarkson, J. E. (2019). Home use of interdental cleaning devices, in addition to toothbrushing, for preventing and controlling periodontal diseases and dental caries. Cochrane Database of Systematic Reviews, 4(4), CD012018. https://doi.org/10.1002/14651858.CD012018.pub2
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247 Health News Editorial
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