NEURO Trial: Novel EEG-Based Prognostication Method for Comatose Patients in ICU — Detecting Cognitive-Motor Dissociation
247 Health News Editorial
·6 Apr 2026
·3 min read
·clinical-trialsThe NEURO trial investigates a novel EEG-based technique to detect cognitive-motor dissociation in comatose ICU patients. This innovative approach could revolutionise prognostication by identifying preserved cognitive function in apparently unresponsive patients following cerebrovascular events.
Originally reported by ClinicalTrials.gov
References
- 1.Claassen, J., Doyle, K., Matory, A., Couch, C., Burger, K. M., Velazquez, A., ... & Schiff, N. D. (2019). Detection of brain activation in unresponsive patients with acute brain injury. New England Journal of Medicine, 380(26), 2497-2505. https://doi.org/10.1056/NEJMoa1812757
- 2.Owen, A. M., Coleman, M. R., Boly, M., Davis, M. H., Laureys, S., & Pickard, J. D. (2006). Detecting awareness in the vegetative state. Science, 313(5792), 1402. https://doi.org/10.1126/science.1130197
- 3.Schiff, N. D. (2015). Cognitive motor dissociation following severe brain injuries. JAMA Neurology, 72(12), 1413-1415. https://doi.org/10.1001/jamaneurol.2015.2899
- 4.Turgeon, A. F., Lauzier, F., Simard, J. F., Scales, D. C., Burns, K. E., Moore, L., ... & Fergusson, D. A. (2011). Mortality associated with withdrawal of life-sustaining therapy for patients with severe traumatic brain injury: A Canadian multicentre cohort study. CMAJ, 183(14), 1581-1588. https://doi.org/10.1503/cmaj.101786
- 5.University Hospital, Bordeaux. (2024). NEURO - Prognostication Using Late Somatosensory Evoked - Potentials. ClinicalTrials.gov. NCT07506928. https://clinicaltrials.gov/study/NCT07506928
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247 Health News Editorial
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