Multi-Centre Trial Evaluates Digital Screening Tools vs Clinical Assessment for Periodontal Disease Detection — 2,000 Patient Study
247 Health News Editorial
·5 May 2026
·4 min read
·clinical-trialsInternational diagnostic accuracy study evaluates digital screening tools including imaging, biomarkers, and questionnaires against clinical examination for detecting periodontal disease. 2,000 participants across multiple centres will validate non-invasive screening approaches.
Originally reported by ClinicalTrials.gov
References
- 1.Australian Institute of Health and Welfare. (2020). Oral health and dental care in Australia (AIHW-DEN-231). https://www.aihw.gov.au/reports/dental-oral-health/oral-health-and-dental-care-in-australia
- 2.Bossuyt, P. M., Reitsma, J. B., Bruns, D. E., Gatsonis, C. A., Glasziou, P. P., Irwig, L., Lijmer, J. G., Glas, A. S., Dowton, S. B., de Vet, H. C., & Cohen, J. F. (2015). STARD 2015: an updated list of essential items for reporting diagnostic accuracy studies. BMJ, 351, h5527. https://doi.org/10.1136/bmj.h5527
- 3.Caton, J. G., Armitage, G., Berglundh, T., Chapple, I. L., Jepsen, S., Kornman, K. S., Mealey, B. L., Papapanou, P. N., Sanz, M., & Tonetti, M. S. (2018). A new classification scheme for periodontal and peri‐implant diseases and conditions. Journal of Periodontology, 89(S1), S1-S8. https://doi.org/10.1002/JPER.18-0157
- 4.Kassebaum, N. J., Bernabé, E., Dahiya, M., Bhandari, B., Murray, C. J., & Marcenes, W. (2014). Global burden of severe periodontitis in 1990-2010: a systematic review and meta-regression. Journal of Dental Research, 93(11), 1045-1053. https://doi.org/10.1177/0022034514552491
- 5.Krois, J., Ekert, T., Meinhold, L., Golla, T., Kharbot, B., Wittemeier, A., Dörfer, C., & Schwendicke, F. (2019). Deep learning for the radiographic detection of periodontal bone loss. Scientific Reports, 9(1), 8495. https://doi.org/10.1038/s41598-019-44839-3
- 6.Sanz, M., Ceriello, A., Buysschaert, M., Chapple, I., Demmer, R. T., Graziani, F., Herrera, D., Jepsen, S., Lione, L., Madianos, P., Mathur, M., Montanya, E., Shapira, L., Tonetti, M., & Vegh, D. (2018). Scientific evidence on the links between periodontal diseases and diabetes: Consensus report and guidelines of the joint workshop on periodontal diseases and diabetes. Journal of Clinical Periodontology, 45(2), 138-149. https://doi.org/10.1111/jcpe.12808
- 7.Shanghai Ninth People's Hospital. (2024). Diagnostic Accuracy of Oral Images, Orthopantomographs (OPGs), Biomarkers and Self-Reported Questionnaires vs. Clinical Assessment for Detecting Periodontal Health and Disease: a Multi-center Diagnostic Study. ClinicalTrials.gov. NCT07406867. https://clinicaltrials.gov/study/NCT07406867
- 8.Tonetti, M. S., Greenwell, H., & Kornman, K. S. (2018). Staging and grading of periodontitis: Framework and proposal of a new classification and case definition. Journal of Periodontology, 89(S1), S159-S172. https://doi.org/10.1002/JPER.18-0006
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247 Health News Editorial
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