Health Technology/clinical-trials

Massive 10-Million Patient Study Develops Blood-Based Pan-Cancer Screening Model — Clinical Implications for Early Detection

247 Health News Editorial

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3 May 2026

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4 min read

·clinical-trials

A groundbreaking 10-million patient retrospective study from China develops machine learning models to detect multiple cancer types using routine blood tests. This research could revolutionise population-based cancer screening through accessible, cost-effective blood biomarker analysis.

Originally reported by ClinicalTrials.gov

References

  1. 1.Chen, X., Gole, J., Gore, A., He, Q., Lu, M., Min, J., Yuan, Z., Yang, X., Jiang, Y., Zhang, T., Suo, C., Li, X., Cheng, L., Zhang, Z., Zhang, H., Xiao, M., Li, Y., Mu, D., Huang, H., ... Weissleder, R. (2020). Non-invasive early detection of cancer four years before conventional diagnosis using a blood test. Nature Communications, 11(1), 3475. https://doi.org/10.1038/s41467-020-17316-z
  2. 2.Schiffman, M., Castle, P. E., Jeronimo, J., Rodriguez, A. C., & Wacholder, S. (2007). Human papillomavirus and cervical cancer. The Lancet, 370(9590), 890-907. https://doi.org/10.1016/S0140-6736(07)61416-0
  3. 3.Smith, R. A., Andrews, K. S., Brooks, D., Fedewa, S. A., Manassaram‐Baptiste, D., Saslow, D., & Wender, R. C. (2019). Cancer screening in the United States, 2019: A review of current American Cancer Society guidelines and current issues in cancer screening. CA: A Cancer Journal for Clinicians, 69(3), 184-210. https://doi.org/10.3322/caac.21557
  4. 4.Sung, H., Ferlay, J., Siegel, R. L., Laversanne, M., Soerjomataram, I., Jemal, A., & Bray, F. (2021). Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA: A Cancer Journal for Clinicians, 71(3), 209-249. https://doi.org/10.3322/caac.21660
  5. 5.Zhejiang Cancer Hospital. (2024). Establishment of a Pan-Cancer Screening Model Based on Blood Biomarkers. ClinicalTrials.gov. NCT07554157. https://clinicaltrials.gov/study/NCT07554157
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247 Health News Editorial

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