Massive 10-Million Patient Study Develops Blood-Based Pan-Cancer Screening Model — Clinical Implications for Early Detection
247 Health News Editorial
·3 May 2026
·4 min read
·clinical-trialsA groundbreaking 10-million patient retrospective study from China develops machine learning models to detect multiple cancer types using routine blood tests. This research could revolutionise population-based cancer screening through accessible, cost-effective blood biomarker analysis.
Originally reported by ClinicalTrials.gov
References
- 1.Chen, X., Gole, J., Gore, A., He, Q., Lu, M., Min, J., Yuan, Z., Yang, X., Jiang, Y., Zhang, T., Suo, C., Li, X., Cheng, L., Zhang, Z., Zhang, H., Xiao, M., Li, Y., Mu, D., Huang, H., ... Weissleder, R. (2020). Non-invasive early detection of cancer four years before conventional diagnosis using a blood test. Nature Communications, 11(1), 3475. https://doi.org/10.1038/s41467-020-17316-z
- 2.Schiffman, M., Castle, P. E., Jeronimo, J., Rodriguez, A. C., & Wacholder, S. (2007). Human papillomavirus and cervical cancer. The Lancet, 370(9590), 890-907. https://doi.org/10.1016/S0140-6736(07)61416-0
- 3.Smith, R. A., Andrews, K. S., Brooks, D., Fedewa, S. A., Manassaram‐Baptiste, D., Saslow, D., & Wender, R. C. (2019). Cancer screening in the United States, 2019: A review of current American Cancer Society guidelines and current issues in cancer screening. CA: A Cancer Journal for Clinicians, 69(3), 184-210. https://doi.org/10.3322/caac.21557
- 4.Sung, H., Ferlay, J., Siegel, R. L., Laversanne, M., Soerjomataram, I., Jemal, A., & Bray, F. (2021). Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA: A Cancer Journal for Clinicians, 71(3), 209-249. https://doi.org/10.3322/caac.21660
- 5.Zhejiang Cancer Hospital. (2024). Establishment of a Pan-Cancer Screening Model Based on Blood Biomarkers. ClinicalTrials.gov. NCT07554157. https://clinicaltrials.gov/study/NCT07554157
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247 Health News Editorial
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