MASAI Study Completed: AI-Enhanced Mammography Screening Shows Promise in 100,000-Woman Trial — Implications for Australian Breast Cancer Screening
247 Health News Editorial
·4 Apr 2026
·3 min read
·clinical-trialsThe MASAI study, involving 100,000 women, has completed evaluation of AI-enhanced mammography screening versus conventional double reading. Results expected in early 2025 could reshape breast cancer screening protocols globally, including Australia's BreastScreen programs.
Originally reported by ClinicalTrials.gov
References
- 1.Australian Institute of Health and Welfare. (2024). BreastScreen Australia monitoring report 2024. AIHW. https://www.aihw.gov.au/reports/cancer-screening/breastscreen-australia-monitoring-report-2024
- 2.Burnside, E. S., Sickles, E. A., Bassett, L. W., Rubin, D. L., Lee, C. H., Ikeda, D. M., Mendelson, E. B., Wilcox, P. A., Butler, P. F., & D'Orsi, C. J. (2009). The ACR BI-RADS experience: learning from history. Journal of the American College of Radiology, 6(12), 851-860. https://doi.org/10.1016/j.jacr.2009.03.023
- 3.Department of Health and Aged Care. (2023). Medical Services Advisory Committee: Guidelines for the assessment of diagnostic technologies. Australian Government. https://www.health.gov.au/committees-and-groups/medical-services-advisory-committee-msac
- 4.Hofvind, S., Ponti, A., Patnick, J., Ascunce, N., Njor, S., Broeders, M., Giordano, L., Frigerio, A., Törnberg, S., Düffy, S., Lynge, E., & Olsen, A. H. (2012). False-positive results in mammographic screening for breast cancer in Europe: a literature review and survey of service screening programmes. Journal of Medical Screening, 19(2), 57-66. https://doi.org/10.1258/jms.2012.012083
- 5.Lång, K., Dustler, M., Dahlblom, V., Åkesson, A., Andersson, I., Zackrisson, S., & Tingberg, A. (2023). Identifying normal mammograms in a large screening population using artificial intelligence. European Radiology, 33(3), 1710-1717. https://doi.org/10.1007/s00330-022-09200-7
- 6.McKinney, S. M., Sieniek, M., Godbole, V., Godwin, J., Antropova, N., Ashrafian, H., Back, T., Chesus, M., Corrado, G. C., Darzi, A., Etemadi, M., Garcia-Vicente, F., Gilbert, F. J., Halling-Brown, M., Hassabis, D., Jansen, S., Karthikesalingam, A., Kelly, C. J., King, D., ... Shetty, S. (2020). International evaluation of an AI system for breast cancer screening. Nature, 577(7788), 89-94. https://doi.org/10.1038/s41586-019-1799-6
- 7.Region Skane. (2024). A Randomized, Single-blinded, Controlled Trial on the Efficacy of Mammography Screening With Artificial Intelligence - the MASAI Study. ClinicalTrials.gov. https://clinicaltrials.gov/study/NCT04838756
- 8.Salim, M., Wåhlin, E., Dembrower, K., Azavedo, E., Foukakis, T., Liu, Y., Smith, K., Eklund, M., & Strand, F. (2020). External evaluation of 3 commercial artificial intelligence algorithms for independent assessment of screening mammograms. JAMA Oncology, 6(10), 1581-1588. https://doi.org/10.1001/jamaoncol.2020.3321
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247 Health News Editorial
247 Health News is a medical intelligence platform delivering evidence-based research appraisals, clinical trial monitoring, and health technology news for healthcare professionals.
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