Health Technology/clinical-trials

Major RCT Evaluates Virtual Sexual Health Education for Adolescents — 1,200 Youth Study Targets Unprotected Sex Reduction

247 Health News Editorial

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21 May 2026

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4 min read

·clinical-trials

A major US trial is evaluating whether virtual sexual health education can reduce risky behaviours in 1,200 adolescents. The 'Yes and Know' program combines group sessions with digital tools, measuring outcomes over 12 months.

Originally reported by ClinicalTrials.gov

References

  1. 1.Centers for Disease Control and Prevention. (2023). Sexually transmitted disease surveillance 2022. US Department of Health and Human Services. https://www.cdc.gov/std/statistics/2022/default.htm
  2. 2.ETR Associates. (2024). Rigorous evaluation of yes and know, a fully virtual intervention integrating group-based education with digital tools to improve youth sexual health and well-being. ClinicalTrials.gov. https://clinicaltrials.gov/study/NCT06581536
  3. 3.Fonner, V. A., Armstrong, K. S., Kennedy, C. E., O'Reilly, K. R., & Sweat, M. D. (2014). School based sex education and HIV prevention in low- and middle-income countries: A systematic review and meta-analysis. PLoS One, 9(3), e89692. https://doi.org/10.1371/journal.pone.0089692
  4. 4.Goldfarb, E. S., & Lieberman, L. D. (2021). Three decades of research: The case for comprehensive sex education. Journal of School Health, 91(1), 13-27. https://doi.org/10.1111/josh.12940
  5. 5.Kirby, D., Laris, B. A., & Rolleri, L. A. (2007). Sex and HIV education programs: Their impact on sexual behaviors of young people throughout the world. Journal of Adolescent Health, 40(3), 206-217. https://doi.org/10.1016/j.jadohealth.2006.11.143
  6. 6.Mason-Jones, A. J., Sinclair, D., Mathews, C., Kagee, A., Hillman, A., & Lombard, C. (2016). School-based interventions for preventing HIV, sexually transmitted infections, and pregnancy in adolescents. Cochrane Database of Systematic Reviews, 11(11), CD006417. https://doi.org/10.1002/14651858.CD006417.pub3
  7. 7.Nagata, J. M., Abdel Magid, H. S., & Gabriel, K. P. (2020). Screen time for children and adolescents during the coronavirus disease 2019 pandemic. Obesity, 28(9), 1582-1583. https://doi.org/10.1002/oby.22917
  8. 8.Schulz, K. F., Altman, D. G., & Moher, D. (2010). CONSORT 2010 statement: Updated guidelines for reporting parallel group randomised trials. BMJ, 340, c332. https://doi.org/10.1136/bmj.c332
  9. 9.Steinberg, L. (2013). The influence of neuroscience on US Supreme Court decisions about adolescents' criminal culpability. Nature Reviews Neuroscience, 14(7), 513-518. https://doi.org/10.1038/nrn3509
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247 Health News Editorial

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