Large-Scale EMR Decision Support Trial Targets Inpatient Glucose Management — 15,000+ Patient Study Could Transform Hospital Diabetes Care
247 Health News Editorial
·23 May 2026
·3 min read
·clinical-trialsA landmark 15,000+ patient study is evaluating electronic medical record clinical decision support for hospital glucose management. The multi-site trial could transform inpatient diabetes care through automated, evidence-based clinical guidance.
Originally reported by ClinicalTrials.gov
References
- 1.Milton S. Hershey Medical Center. (2024). Glucose Management Clinical Decision Support to Improve Outcomes in Academic and Community Hospitals. ClinicalTrials.gov. NCT05447806. https://clinicaltrials.gov/study/NCT05447806
- 2.Bally, L., Thabit, H., Hartnell, S., Andereggen, E., Ruan, Y., Wilinska, M. E., Evans, M. L., Wertli, M. M., Coll, A. P., Stettler, C., & Hovorka, R. (2018). Closed-loop insulin delivery for glycemic control in noncritical care. New England Journal of Medicine, 379(6), 547-556. https://doi.org/10.1056/NEJMoa1805233
- 3.Hemkens, L. G., Contopoulos-Ioannidis, D. G., & Ioannidis, J. P. (2016). Agreement of treatment effects for mortality from routinely collected data and subsequent randomized trials. JAMA, 316(15), 1599-1607. https://doi.org/10.1001/jama.2016.8762
- 4.Bright, T. J., Wong, A., Dhurjati, R., Bristow, E., Bastian, L., Coeytaux, R. R., Samsa, G., Hasselblad, V., Williams, J. W., Musty, M. D., Wing, L., Kendrick, A. S., Sanders, G. D., & Lobach, D. (2012). Effect of clinical decision-support systems: a systematic review. Annals of Internal Medicine, 157(1), 29-43. https://doi.org/10.7326/0003-4819-157-1-201207030-00450
- 5.Loudon, K., Treweek, S., Sullivan, F., Donnan, P., Thorpe, K. E., & Zwarenstein, M. (2015). The PRECIS-2 tool: designing trials that are fit for purpose. BMJ, 350, h2147. https://doi.org/10.1136/bmj.h2147
- 6.Umpierrez, G. E., Isaacs, S. D., Bazargan, N., You, X., Thaler, L. M., & Kitabchi, A. E. (2002). Hyperglycemia: an independent marker of in-hospital mortality in patients with undiagnosed diabetes. Journal of Clinical Endocrinology & Metabolism, 87(3), 978-982. https://doi.org/10.1210/jcem.87.3.8341
- 7.Moghissi, E. S., Korytkowski, M. T., DiNardo, M., Einhorn, D., Hellman, R., Hirsch, I. B., Inzucchi, S. E., Ismail-Beigi, F., Kirkman, M. S., & Umpierrez, G. E. (2009). American Association of Clinical Endocrinologists and American Diabetes Association consensus statement on inpatient glycemic control. Diabetes Care, 32(6), 1119-1131. https://doi.org/10.2337/dc09-9029
- 8.Rubin, D. J., Rybin, D., Doros, G., & McDonnell, M. E. (2014). Weight-based, insulin-related hypoglycemia in hospitalized patients with diabetes. Diabetes Care, 37(12), 3424-3432. https://doi.org/10.2337/dc13-2204
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247 Health News Editorial
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