Health Technology/clinical-trials

Large-Scale EMR Decision Support Trial Targets Inpatient Glucose Management — 15,000+ Patient Study Could Transform Hospital Diabetes Care

247 Health News Editorial

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23 May 2026

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3 min read

·clinical-trials

A landmark 15,000+ patient study is evaluating electronic medical record clinical decision support for hospital glucose management. The multi-site trial could transform inpatient diabetes care through automated, evidence-based clinical guidance.

Originally reported by ClinicalTrials.gov

References

  1. 1.Milton S. Hershey Medical Center. (2024). Glucose Management Clinical Decision Support to Improve Outcomes in Academic and Community Hospitals. ClinicalTrials.gov. NCT05447806. https://clinicaltrials.gov/study/NCT05447806
  2. 2.Bally, L., Thabit, H., Hartnell, S., Andereggen, E., Ruan, Y., Wilinska, M. E., Evans, M. L., Wertli, M. M., Coll, A. P., Stettler, C., & Hovorka, R. (2018). Closed-loop insulin delivery for glycemic control in noncritical care. New England Journal of Medicine, 379(6), 547-556. https://doi.org/10.1056/NEJMoa1805233
  3. 3.Hemkens, L. G., Contopoulos-Ioannidis, D. G., & Ioannidis, J. P. (2016). Agreement of treatment effects for mortality from routinely collected data and subsequent randomized trials. JAMA, 316(15), 1599-1607. https://doi.org/10.1001/jama.2016.8762
  4. 4.Bright, T. J., Wong, A., Dhurjati, R., Bristow, E., Bastian, L., Coeytaux, R. R., Samsa, G., Hasselblad, V., Williams, J. W., Musty, M. D., Wing, L., Kendrick, A. S., Sanders, G. D., & Lobach, D. (2012). Effect of clinical decision-support systems: a systematic review. Annals of Internal Medicine, 157(1), 29-43. https://doi.org/10.7326/0003-4819-157-1-201207030-00450
  5. 5.Loudon, K., Treweek, S., Sullivan, F., Donnan, P., Thorpe, K. E., & Zwarenstein, M. (2015). The PRECIS-2 tool: designing trials that are fit for purpose. BMJ, 350, h2147. https://doi.org/10.1136/bmj.h2147
  6. 6.Umpierrez, G. E., Isaacs, S. D., Bazargan, N., You, X., Thaler, L. M., & Kitabchi, A. E. (2002). Hyperglycemia: an independent marker of in-hospital mortality in patients with undiagnosed diabetes. Journal of Clinical Endocrinology & Metabolism, 87(3), 978-982. https://doi.org/10.1210/jcem.87.3.8341
  7. 7.Moghissi, E. S., Korytkowski, M. T., DiNardo, M., Einhorn, D., Hellman, R., Hirsch, I. B., Inzucchi, S. E., Ismail-Beigi, F., Kirkman, M. S., & Umpierrez, G. E. (2009). American Association of Clinical Endocrinologists and American Diabetes Association consensus statement on inpatient glycemic control. Diabetes Care, 32(6), 1119-1131. https://doi.org/10.2337/dc09-9029
  8. 8.Rubin, D. J., Rybin, D., Doros, G., & McDonnell, M. E. (2014). Weight-based, insulin-related hypoglycemia in hospitalized patients with diabetes. Diabetes Care, 37(12), 3424-3432. https://doi.org/10.2337/dc13-2204
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247 Health News Editorial

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