Landmark Digital Trial Opens: Smartphone-Based AF Screening vs Usual Care in 100,000 Older Adults — Stroke Prevention at Population Scale
247 Health News Editorial
·25 July 2026
·5 min read
·clinical-trialsThe Austrian Digital Heart Study (NCT07684053) is enrolling 100,060 adults aged 65 and over to test whether smartphone-based AF screening using the 'Pulskontrolle' app reduces stroke hospitalisations compared with usual care. With a 48-month follow-up and hard clinical endpoints, this siteless randomised trial could redefine population-level AF detection strategies globally.
Originally reported by ClinicalTrials.gov
References
- 1.Medical University of Innsbruck. (2025). Digital screening for atrial fibrillation to prevent stroke: The randomized Austrian Digital Heart Study (NCT07684053). ClinicalTrials.gov. https://clinicaltrials.gov/study/NCT07684053
- 2.Lippi, G., Sanchis-Gomar, F., & Cervellin, G. (2021). Global epidemiology of atrial fibrillation: An increasing epidemic and public health challenge. International Journal of Stroke, 16(2), 217–221. https://doi.org/10.1177/1747493019897870
- 3.Hindricks, G., Potpara, T., Dagres, N., Arbelo, E., Bax, J. J., Blomström-Lundqvist, C., Boriani, G., Castella, M., Dan, G. A., Dilaveris, P. E., Fauchier, L., Filippatos, G., Kalman, J. M., La Meir, M., Lane, D. A., Lebeau, J. P., Lettino, M., Lip, G. Y. H., Pinto, F. J., … ESC Scientific Document Group. (2021). 2020 ESC Guidelines for the diagnosis and management of atrial fibrillation developed in collaboration with the European Association for Cardio-Thoracic Surgery (EACTS). European Heart Journal, 42(5), 373–498. https://doi.org/10.1093/eurheartj/ehaa612
- 4.Perez, M. V., Mahaffey, K. W., Hedlin, H., Rumsfeld, J. S., Garcia, A., Ferris, T., Balasubramanian, V., Russo, A. M., Rajmane, A., Cheung, L., Hung, G., Lee, J., Kowey, P., Talati, N., Nag, D., Gummidipundi, S. E., Beatty, A., Hills, M. T., Desai, S., … Turakhia, M. P. (2019). Large-scale assessment of a smartwatch to identify atrial fibrillation. New England Journal of Medicine, 381(20), 1909–1917. https://doi.org/10.1056/NEJMoa1901183
- 5.Freedman, B., Camm, J., Calkins, H., Healey, J. S., Rosenqvist, M., Wang, J., Albert, C. M., Anderson, C. S., Antoniou, S., Benjamin, E. J., Boriani, G., Brachmann, J., Brandes, A., Chao, T. F., Conen, D., Engdahl, J., Fauchier, L., Fitzmaurice, D. A., Friberg, L., … AF-Screen International Collaboration. (2017). Screening for atrial fibrillation: A report of the AF-Screen International Collaboration. Circulation, 135(19), 1851–1867. https://doi.org/10.1161/CIRCULATIONAHA.116.026693
- 6.Lowres, N., Neubeck, L., Redfern, J., & Freedman, S. B. (2013). Screening to identify unknown atrial fibrillation: A systematic review. Thrombosis and Haemostasis, 110(2), 213–222. https://doi.org/10.1160/TH13-02-0165
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247 Health News Editorial
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