Health Technology/clinical-trials

Landmark AI Study Targets IOL Calculation Accuracy in High Myopia Cataract Surgery — 500,000 Patient Registry Opens

247 Health News Editorial

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17 May 2026

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4 min read

·clinical-trials

A groundbreaking 500,000-patient registry study is developing advanced AI models to improve IOL power calculation accuracy in highly myopic cataract surgery. The Shanghai High Myopia Study Group aims to address the significant challenge of refractive surprises in this complex patient population.

Originally reported by ClinicalTrials.gov

References

  1. 1.Aristodemou, P., Knox Cartwright, N. E., Sparrow, J. M., & Johnston, R. L. (2011). Formula choice: Hoffer Q, Holladay 1, or SRK/T and refractive outcomes in 8108 eyes after cataract surgery with biometry by partial coherence interferometry. Journal of Cataract & Refractive Surgery, 37(1), 63-71. https://doi.org/10.1016/j.jcrs.2010.07.032
  2. 2.Cooke, D. L., & Cooke, T. L. (2016). Comparison of 9 intraocular lens power calculation formulas. Journal of Cataract & Refractive Surgery, 42(8), 1157-1164. https://doi.org/10.1016/j.jcrs.2015.11.034
  3. 3.French, A. N., Ashby, R. S., Morgan, I. G., & Rose, K. A. (2013). Time outdoors and the prevention of myopia. Experimental Eye Research, 114, 58-68. https://doi.org/10.1016/j.exer.2013.04.018
  4. 4.Holden, B. A., Fricke, T. R., Wilson, D. A., Jong, M., Naidoo, K. S., Sankaridurg, P., ... & Resnikoff, S. (2016). Global prevalence of myopia and high myopia and temporal trends from 2000 through 2050. Ophthalmology, 123(5), 1036-1042. https://doi.org/10.1016/j.ophtha.2016.01.006
  5. 5.Kane, J. X., Van Heerden, A., Atik, A., & Petsoglou, C. (2016). Intraocular lens power formula accuracy: Comparison of 7 formulas. Journal of Cataract & Refractive Surgery, 42(10), 1490-1500. https://doi.org/10.1016/j.jcrs.2016.06.029
  6. 6.Melles, R. B., Holladay, J. T., & Chang, W. J. (2018). Accuracy of intraocular lens calculation formulas. Ophthalmology, 125(2), 169-178. https://doi.org/10.1016/j.ophtha.2017.08.027
  7. 7.Shanghai High Myopia Study Group. (2024). Artificial Intelligence for Highly Myopic Cataract. ClinicalTrials.gov. NCT06616506. https://clinicaltrials.gov/study/NCT06616506
  8. 8.Wang, L., Koch, D. D., Hill, W., & Abulafia, A. (2021). Pursuing perfection in intraocular lens calculations: III. Criteria for analyzing outcomes. Journal of Cataract & Refractive Surgery, 47(2), 180-185. https://doi.org/10.1097/j.jcrs.0000000000000692
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